Drawing recently discovered near Khomein show among other engravings a person riding a horse with archery. Based on Dutch archeologists some of the engravings are up to 40,000 years old.
Link1, link2.
Courtesy from AFP
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Sunday, December 11, 2016
Thursday, December 1, 2016
Enattah et al., 2008: Convergence of lactase persistence
Today, I want to dig a little bit more into the genetics of lactase persistence. The goal is still to identify unknown MCM6 haplotypes in Middle Eastern populations that could lead to lactose tolerance and to identify the root of the known MCM6 haplotypes that result in lactase persistence.
Previously, I postulated the following phylogentic tree for the MCM6 gene (based on 23andme data):
I used genetic data from Enattah et al., 2008 and identified 9 SNP of MCM6 that are also tested at 23andme. Based on these 9 SNPs I identified ht1-6, the Saudi-Arabian lactase persistence (ht8), the East African lactase persistence (ht13), and several more. You can download the table here.
In the table above it becomes obvious that Saudi-Arabian lactase persistence (ht8) is derived from ht5, both share "C" at rs4988243. The European lactase persistence (ht3) is derived from ht2, and the East African lactase persistence (ht15) is derived from ht1.
From the paper, Enattah et al., 2008:
I also added the Kurdish data to this table. You can download the table here:
In Eurasia, the vast majority are ht1 to ht6. In Africa, the MCM6 gene is more diverse.
Not surprisingly, Kurds show similarities with Iranians in their MCM6 repertoire and frequencies.
Since these haplotypes are just based on 9 SNPs they are less reliable, I decided to expand the number of SNPs gradually. To define further SNPs of the Saudi-Arabian lactase persistence I asked several Saudi-Arabians to participate in a small survey. I could confirm that the Saudi-Arabian lactase persistence (ht8) is derived from ht5 and correlates with the expected phenotype (=lactose tolerant). I also observed ht13 in one individual and added both data (ht8 and ht13) in the expanded list of SNPs that can be checked on 23andme. The other haplotypes are extracted (ht9-12, ht14-18) are extracted from Enattah et al., 2008.
You can download the table here:
Related post:
Lactose intolerance: Six MCM6 variants in the Kurdish gene pool / Why 22018A is strongly, but not completely related to lactase persistence
Lactose Tolerance
Previously, I postulated the following phylogentic tree for the MCM6 gene (based on 23andme data):
I used genetic data from Enattah et al., 2008 and identified 9 SNP of MCM6 that are also tested at 23andme. Based on these 9 SNPs I identified ht1-6, the Saudi-Arabian lactase persistence (ht8), the East African lactase persistence (ht13), and several more. You can download the table here.
In the table above it becomes obvious that Saudi-Arabian lactase persistence (ht8) is derived from ht5, both share "C" at rs4988243. The European lactase persistence (ht3) is derived from ht2, and the East African lactase persistence (ht15) is derived from ht1.
From the paper, Enattah et al., 2008:
The European T(-13910) and the earlier identified East African G(-13907) LP allele share the same ancestral background and most likely the same history, probably related to the same cattle domestication event. In contrast, the compound Arab allele shows a different, highly divergent ancestral haplotype, suggesting that these two major global LP alleles have arisen independently, the latter perhaps in response to camel milk consumption. These results support the convergent evolution of the LP in diverse populations, most probably reflecting different histories of adaptation to milk culture.Previously, I showed that Kurds, Iraqi Jews and Pakistanis have ht2. Now, I could show that ht2 is also present in Arabs from the Middle East and the Kalash. I determined frequencies of these haplotypes based on data from Enattah et al., 2008.
I also added the Kurdish data to this table. You can download the table here:
In Eurasia, the vast majority are ht1 to ht6. In Africa, the MCM6 gene is more diverse.
Not surprisingly, Kurds show similarities with Iranians in their MCM6 repertoire and frequencies.
Since these haplotypes are just based on 9 SNPs they are less reliable, I decided to expand the number of SNPs gradually. To define further SNPs of the Saudi-Arabian lactase persistence I asked several Saudi-Arabians to participate in a small survey. I could confirm that the Saudi-Arabian lactase persistence (ht8) is derived from ht5 and correlates with the expected phenotype (=lactose tolerant). I also observed ht13 in one individual and added both data (ht8 and ht13) in the expanded list of SNPs that can be checked on 23andme. The other haplotypes are extracted (ht9-12, ht14-18) are extracted from Enattah et al., 2008.
You can download the table here:
Related post:
Lactose intolerance: Six MCM6 variants in the Kurdish gene pool / Why 22018A is strongly, but not completely related to lactase persistence
Lactose Tolerance
Friday, June 12, 2015
Dodecad K12b values of Bronze Age individuals living in Armenia
A new paper in Nature (Allentoft et al., 2015) presenting the genomes of ancient 101 Eurasians is currently fascinating geneticists but also linguists and historians. Some of these tested Bronze Age individuals lived in nowadays Armenia.
Here, I want to use their Dodecad K12b values (shared by Mfa from Corduene.blogspot.com) to calculate the closest reference populations for these individuals. Most of the tested individuals from Armenia can be resembled the best as 50-75% Iranian (including Kurds) or Lezgin and 25-50% European. In most cases, Kurds and especially Zaza are among the Top10 reference populations for these ancient genomes, see data below.
In terms of genetic composition the Southern Caucasus was more Iranian-like and European-like than it is today. The shift from Bronze Age to now could be explained by several Semitic empires and three Semitic religions (Judaism, Christianity and Islam) that expanded from South to North and probably impacted local populations of the Northern Middle East.
Interestingly, when traveling through Kurdistan a phenotypic gradient can be seen depending on the altitude: populations from hidden villages in the higher Mountains appear to have lighter skin (and lighter eye color) than the populations from towns in the valleys. Kurds also claim that in ancient times their people were more fair-skinned than they are today.
I believe the same (more Iranian-like and European-like than it is today) will be seen for genomes from Kurdistan. I also believe that the European-like character South of the Caucasus was introduced before the Neolithic expansion, hopefully, ancient DNA will prove this one day. As I mentioned earlier I believe that R1a and R1b originated in or near Kurdistan; two of the Bronze Age samples from Armenia are R1b (RISE397 and RISE413).
RISE413 MBA (1906 BC):
TOP reference populations based on Dodecad K12b:
1 19.6 Turkmens_Y
2 20.2 Turkish_Aydin_Ho
3 20.7 Zaza_P
4 21.0 Turkish_Istanbul_Ho
5 21.3 Turkish_Kayseri_Ho
6 21.4 Tajiks_Y
7 21.7 Iranians
8 21.9 Iranian_D
9 22.1 Kurd_D
10 22.5 Kurds_Y
Oracle K12B:
# Distance
1 7.2639 69.1% Iranians + 30.9% Orcadian
2 7.2701 69.2% Iranians + 30.8% Orkney_1KG
3 7.2770 69% Iranians + 31% Irish_D
4 7.3007 68% Iranians + 32% CEU30
5 7.3294 68.1% Iranians + 31.9% English_D
6 7.3327 67.9% Kurd_D___ + 32.1% Argyll_1KG
7 7.3436 66.4% Iranians + 33.6% Mixed_Germanic_D
8 7.3579 68.4% Iranians + 31.6% Cornwall_1KG
9 7.3697 67.9% Iranians + 32.1% Kent_1KG
10 7.4109 68.1% Iranian_D + 31.9% Argyll_1KG
RISE416 MBA (1643 BC):
1 16.8 O_Italian_D
2 18.4 TSI30
3 18.5 N_Italian_D
4 18.9 Tuscan
5 19.3 C_Italian_D
6 20.5 North_Italian
7 22.7 S_Italian_Sicilian_D
8 23.2 Greek_D
9 23.4 Sicilian_D
10 24.7 Baleares_1KG
Oracle K12B:
# Distance
1 7.2386 75.3% N_Italian_D + 24.7% Balochi
2 7.4475 74.6% N_Italian_D + 25.4% Makrani
3 7.6021 77% N_Italian_D + 23% Brahui
4 7.6188 77% TSI30 + 23% Brahui
5 7.6521 52.4% Lezgins__ + 47.6% Pais_Vasco_1KG
6 7.6804 55% Kurds_Y___ + 45% Pais_Vasco_1KG
7 7.6909 73.3% North_Italian + 26.7% Balochi
8 7.8920 75.5% TSI30 + 24.5% Balochi
9 7.9160 55.2% Iranian_D + 44.8% Pais_Vasco_1KG
10 7.9334 72.6% North_Italian + 27.4% Makrani
RISE423 MBA (1402 BC):
1 14.8 Kumyks_Y
2 15.5 Turkish_Istanbul_Ho
3 16.1 Lezgins__
4 16.5 Turkish_Aydin_Ho
5 16.8 Turkish_Kayseri_Ho
6 16.9 Zaza_P___
7 18.5 Turks___
8 18.9 Turkish_D
9 19.0 Kurds_Y___
10 19.1 Chechens_Y
Oracle K12B:
# Distance
1 4.6697 73.6% Kurds_Y___ + 26.4% Belorussian
2 4.6825 72.5% Kurds_Y___ + 27.5% Mixed_Slav_D
3 4.7566 72.7% Kurds_Y___ + 27.3% Polish_D
4 4.7988 71.3% Kurds_Y___ + 28.7% Ukranians_Y
5 4.8007 73.2% Kurds_Y___ + 26.8% Russian_D
6 4.9732 75.6% Kurds_Y___ + 24.4% Lithuanian_D
7 4.9897 73.2% Kurd_D___ + 26.8% Belorussian
8 5.0133 76.7% Kurds_Y___ + 23.3% Lithuanians
9 5.0365 70.9% Kurd_D___ + 29.1% Ukranians_Y
10 5.0987 72.1% Kurds_Y___ + 27.9% Mordovians_Y
RISE408 LBA (1209 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 18.0 Lezgins__
2 19.3 Kumyks_Y
3 21.4 Turkish_Istanbul_Ho
4 21.5 Turkish_Aydin_Ho
5 22.0 Chechens_Y
6 22.6 Turkish_Kayseri_Ho
7 22.7 Turkmens_Y
8 23.0 Zaza_P___
9 24.0 Tajiks_Y
10 24.3 Iranian_D
Oracle:
# Distance
1 4.7378 79.2% Lezgins__ + 20.8% French_Basque
2 5.2651 72.7% Lezgins__ + 27.3% Cataluna_1KG
3 5.5218 73.7% Lezgins__ + 26.3% Valencia_1KG
4 5.5712 73.9% Lezgins__ + 26.1% Cantabria_1KG
5 5.5818 74.3% Lezgins__ + 25.7% Aragon_1KG
6 5.6722 73.8% Lezgins__ + 26.2% Castilla_La_Mancha_1KG
7 5.6816 73.3% Lezgins__ + 26.7% Spanish_D
8 5.7200 73% Lezgins__ + 27% Spaniards
9 5.8826 71.1% Lezgins__ + 28.9% French
10 5.9217 71.1% Lezgins__ + 28.9% French_D
RISE412 LBA (1193 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID1 9.6 Adygei
2 11.2 Balkars_Y
3 11.7 Kumyks_Y
4 11.8 North_Ossetians_Y
5 13.1 Chechens_Y
6 13.2 Turks___
7 13.2 Turkish_D
8 14.1 Armenians
9 14.7 Turkish_Istanbul_Ho
10 15.8 Armenians_15_Y
11 16.2 Armenian_D
12 16.4 Turkish_Kayseri_Ho
13 17.5 Lezgins__
14 18.3 Abhkasians_Y
15 18.5 Georgia_Jews
16 18.7 Zaza_P___
Oracle K12B:
# Distance
1 3.6433 77.2% Adygei + 22.8% Sephardic_Jews
2 4.0513 77.5% Adygei + 22.5% S_Italian_Sicilian_D
3 4.0932 76.4% Adygei + 23.6% Ashkenazi_D
4 4.1480 75.4% Adygei + 24.6% Ashkenazy_Jews
5 4.2166 77.9% Adygei + 22.1% Sicilian_D
6 4.2440 80% Adygei + 20% Morocco_Jews
7 4.3430 64.7% Chechens_Y + 35.3% Cypriots
8 4.6281 60.3% Adygei + 39.7% Turkish_D
9 4.8258 75% Adygei + 25% Druze
10 4.9047 75.9% Adygei + 24.1% Lebanese
11 4.9790 84.3% Armenians + 15.7% Lithuanians
12 5.0526 77.3% Adygei + 22.7% Greek_D
13 5.0618 64.2% Abhkasians_Y + 35.8% Bulgarian_D
14 5.0744 82% Armenians + 18% Russian_B
15 5.0939 83.6% Armenians + 16.4% Lithuanian_D
16 5.1290 78.9% Adygei + 21.1% Syrians
17 5.1671 81.7% Armenians + 18.3% Mordovians_Y
18 5.1701 70.9% Balkars_Y + 29.1% Cypriots
19 5.2275 65.7% Abhkasians_Y + 34.3% Romanians
20 5.2709 67.1% Adygei + 32.9% Turkish_Kayseri_Ho
RISE396 LBA (1192 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 12.0 Turkish_Istanbul_Ho
2 12.6 Kumyks_Y
3 13.5 Turkish_Kayseri_Ho
4 14.5 Turkish_Aydin_Ho
5 14.5 Turkish_D
6 14.6 Turks___
7 15.3 Zaza_P___
8 16.1 Lezgins__
9 17.1 Chechens_Y
10 18.1 Kurds_Y___
Oracle K12B:
# Distance
1 4.2060 58.2% Lezgins__ + 41.8% Greek_D
2 4.4492 61.5% Lezgins__ + 38.5% Sicilian_D
3 4.5387 60.3% Lezgins__ + 39.7% Ashkenazi_D
4 4.7105 63.8% Lezgins__ + 36.2% C_Italian_D
5 4.7696 58.9% Lezgins__ + 41.1% Ashkenazy_Jews
6 5.2481 63.3% Lezgins__ + 36.7% O_Italian_D
7 5.4614 66.2% Lezgins__ + 33.8% Tuscan
8 5.5673 67% Lezgins__ + 33% TSI30
9 5.8915 62.9% Lezgins__ + 37.1% Sephardic_Jews
10 6.0393 58% Kurds_Y___ + 42% Bulgarian_D
RISE407 LBA (1115 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 19.1 Lezgins__
2 19.6 Turkmens_Y
3 20.0 Tajiks_Y
4 20.7 Kumyks_Y
5 21.3 Zaza_P___
6 21.6 Turkish_Aydin_Ho
7 21.7 Turkish_Istanbul_Ho
8 22.0 Iranian_D
9 22.5 Kurd_D___
10 22.5 Kurds_Y___
Oracle K12B:
# Distance
1 9.0414 77.7% Lezgins__ + 22.3% Pais_Vasco_1KG
2 9.1657 70.8% Iranian_D + 29.2% Norwegian_D
3 9.4091 70.2% Kurd_D___ + 29.8% Swedish_D
4 9.4630 79.2% Lezgins__ + 20.8% French_Basque
5 9.5599 70.4% Kurd_D___ + 29.6% Norwegian_D
6 9.6359 70.1% Kurds_Y___ + 29.9% Swedish_D
7 9.6374 71.4% Lezgins__ + 28.6% Portuguese_D
8 9.6513 72.7% Lezgins__ + 27.3% Cataluna_1KG
9 9.6726 71.2% Lezgins__ + 28.8% Extremadura_1KG
10 9.6800 73.6% Lezgins__ + 26.4% Castilla_La_Mancha_1KG
Here, I want to use their Dodecad K12b values (shared by Mfa from Corduene.blogspot.com) to calculate the closest reference populations for these individuals. Most of the tested individuals from Armenia can be resembled the best as 50-75% Iranian (including Kurds) or Lezgin and 25-50% European. In most cases, Kurds and especially Zaza are among the Top10 reference populations for these ancient genomes, see data below.
In terms of genetic composition the Southern Caucasus was more Iranian-like and European-like than it is today. The shift from Bronze Age to now could be explained by several Semitic empires and three Semitic religions (Judaism, Christianity and Islam) that expanded from South to North and probably impacted local populations of the Northern Middle East.
Interestingly, when traveling through Kurdistan a phenotypic gradient can be seen depending on the altitude: populations from hidden villages in the higher Mountains appear to have lighter skin (and lighter eye color) than the populations from towns in the valleys. Kurds also claim that in ancient times their people were more fair-skinned than they are today.
I believe the same (more Iranian-like and European-like than it is today) will be seen for genomes from Kurdistan. I also believe that the European-like character South of the Caucasus was introduced before the Neolithic expansion, hopefully, ancient DNA will prove this one day. As I mentioned earlier I believe that R1a and R1b originated in or near Kurdistan; two of the Bronze Age samples from Armenia are R1b (RISE397 and RISE413).
RISE413 MBA (1906 BC):
TOP reference populations based on Dodecad K12b:
1 19.6 Turkmens_Y
2 20.2 Turkish_Aydin_Ho
3 20.7 Zaza_P
4 21.0 Turkish_Istanbul_Ho
5 21.3 Turkish_Kayseri_Ho
6 21.4 Tajiks_Y
7 21.7 Iranians
8 21.9 Iranian_D
9 22.1 Kurd_D
10 22.5 Kurds_Y
Oracle K12B:
# Distance
1 7.2639 69.1% Iranians + 30.9% Orcadian
2 7.2701 69.2% Iranians + 30.8% Orkney_1KG
3 7.2770 69% Iranians + 31% Irish_D
4 7.3007 68% Iranians + 32% CEU30
5 7.3294 68.1% Iranians + 31.9% English_D
6 7.3327 67.9% Kurd_D___ + 32.1% Argyll_1KG
7 7.3436 66.4% Iranians + 33.6% Mixed_Germanic_D
8 7.3579 68.4% Iranians + 31.6% Cornwall_1KG
9 7.3697 67.9% Iranians + 32.1% Kent_1KG
10 7.4109 68.1% Iranian_D + 31.9% Argyll_1KG
RISE416 MBA (1643 BC):
1 16.8 O_Italian_D
2 18.4 TSI30
3 18.5 N_Italian_D
4 18.9 Tuscan
5 19.3 C_Italian_D
6 20.5 North_Italian
7 22.7 S_Italian_Sicilian_D
8 23.2 Greek_D
9 23.4 Sicilian_D
10 24.7 Baleares_1KG
Oracle K12B:
# Distance
1 7.2386 75.3% N_Italian_D + 24.7% Balochi
2 7.4475 74.6% N_Italian_D + 25.4% Makrani
3 7.6021 77% N_Italian_D + 23% Brahui
4 7.6188 77% TSI30 + 23% Brahui
5 7.6521 52.4% Lezgins__ + 47.6% Pais_Vasco_1KG
6 7.6804 55% Kurds_Y___ + 45% Pais_Vasco_1KG
7 7.6909 73.3% North_Italian + 26.7% Balochi
8 7.8920 75.5% TSI30 + 24.5% Balochi
9 7.9160 55.2% Iranian_D + 44.8% Pais_Vasco_1KG
10 7.9334 72.6% North_Italian + 27.4% Makrani
RISE423 MBA (1402 BC):
1 14.8 Kumyks_Y
2 15.5 Turkish_Istanbul_Ho
3 16.1 Lezgins__
4 16.5 Turkish_Aydin_Ho
5 16.8 Turkish_Kayseri_Ho
6 16.9 Zaza_P___
7 18.5 Turks___
8 18.9 Turkish_D
9 19.0 Kurds_Y___
10 19.1 Chechens_Y
Oracle K12B:
# Distance
1 4.6697 73.6% Kurds_Y___ + 26.4% Belorussian
2 4.6825 72.5% Kurds_Y___ + 27.5% Mixed_Slav_D
3 4.7566 72.7% Kurds_Y___ + 27.3% Polish_D
4 4.7988 71.3% Kurds_Y___ + 28.7% Ukranians_Y
5 4.8007 73.2% Kurds_Y___ + 26.8% Russian_D
6 4.9732 75.6% Kurds_Y___ + 24.4% Lithuanian_D
7 4.9897 73.2% Kurd_D___ + 26.8% Belorussian
8 5.0133 76.7% Kurds_Y___ + 23.3% Lithuanians
9 5.0365 70.9% Kurd_D___ + 29.1% Ukranians_Y
10 5.0987 72.1% Kurds_Y___ + 27.9% Mordovians_Y
RISE408 LBA (1209 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 18.0 Lezgins__
2 19.3 Kumyks_Y
3 21.4 Turkish_Istanbul_Ho
4 21.5 Turkish_Aydin_Ho
5 22.0 Chechens_Y
6 22.6 Turkish_Kayseri_Ho
7 22.7 Turkmens_Y
8 23.0 Zaza_P___
9 24.0 Tajiks_Y
10 24.3 Iranian_D
Oracle:
# Distance
1 4.7378 79.2% Lezgins__ + 20.8% French_Basque
2 5.2651 72.7% Lezgins__ + 27.3% Cataluna_1KG
3 5.5218 73.7% Lezgins__ + 26.3% Valencia_1KG
4 5.5712 73.9% Lezgins__ + 26.1% Cantabria_1KG
5 5.5818 74.3% Lezgins__ + 25.7% Aragon_1KG
6 5.6722 73.8% Lezgins__ + 26.2% Castilla_La_Mancha_1KG
7 5.6816 73.3% Lezgins__ + 26.7% Spanish_D
8 5.7200 73% Lezgins__ + 27% Spaniards
9 5.8826 71.1% Lezgins__ + 28.9% French
10 5.9217 71.1% Lezgins__ + 28.9% French_D
RISE412 LBA (1193 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID1 9.6 Adygei
2 11.2 Balkars_Y
3 11.7 Kumyks_Y
4 11.8 North_Ossetians_Y
5 13.1 Chechens_Y
6 13.2 Turks___
7 13.2 Turkish_D
8 14.1 Armenians
9 14.7 Turkish_Istanbul_Ho
10 15.8 Armenians_15_Y
11 16.2 Armenian_D
12 16.4 Turkish_Kayseri_Ho
13 17.5 Lezgins__
14 18.3 Abhkasians_Y
15 18.5 Georgia_Jews
16 18.7 Zaza_P___
Oracle K12B:
# Distance
1 3.6433 77.2% Adygei + 22.8% Sephardic_Jews
2 4.0513 77.5% Adygei + 22.5% S_Italian_Sicilian_D
3 4.0932 76.4% Adygei + 23.6% Ashkenazi_D
4 4.1480 75.4% Adygei + 24.6% Ashkenazy_Jews
5 4.2166 77.9% Adygei + 22.1% Sicilian_D
6 4.2440 80% Adygei + 20% Morocco_Jews
7 4.3430 64.7% Chechens_Y + 35.3% Cypriots
8 4.6281 60.3% Adygei + 39.7% Turkish_D
9 4.8258 75% Adygei + 25% Druze
10 4.9047 75.9% Adygei + 24.1% Lebanese
11 4.9790 84.3% Armenians + 15.7% Lithuanians
12 5.0526 77.3% Adygei + 22.7% Greek_D
13 5.0618 64.2% Abhkasians_Y + 35.8% Bulgarian_D
14 5.0744 82% Armenians + 18% Russian_B
15 5.0939 83.6% Armenians + 16.4% Lithuanian_D
16 5.1290 78.9% Adygei + 21.1% Syrians
17 5.1671 81.7% Armenians + 18.3% Mordovians_Y
18 5.1701 70.9% Balkars_Y + 29.1% Cypriots
19 5.2275 65.7% Abhkasians_Y + 34.3% Romanians
20 5.2709 67.1% Adygei + 32.9% Turkish_Kayseri_Ho
RISE396 LBA (1192 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 12.0 Turkish_Istanbul_Ho
2 12.6 Kumyks_Y
3 13.5 Turkish_Kayseri_Ho
4 14.5 Turkish_Aydin_Ho
5 14.5 Turkish_D
6 14.6 Turks___
7 15.3 Zaza_P___
8 16.1 Lezgins__
9 17.1 Chechens_Y
10 18.1 Kurds_Y___
Oracle K12B:
# Distance
1 4.2060 58.2% Lezgins__ + 41.8% Greek_D
2 4.4492 61.5% Lezgins__ + 38.5% Sicilian_D
3 4.5387 60.3% Lezgins__ + 39.7% Ashkenazi_D
4 4.7105 63.8% Lezgins__ + 36.2% C_Italian_D
5 4.7696 58.9% Lezgins__ + 41.1% Ashkenazy_Jews
6 5.2481 63.3% Lezgins__ + 36.7% O_Italian_D
7 5.4614 66.2% Lezgins__ + 33.8% Tuscan
8 5.5673 67% Lezgins__ + 33% TSI30
9 5.8915 62.9% Lezgins__ + 37.1% Sephardic_Jews
10 6.0393 58% Kurds_Y___ + 42% Bulgarian_D
RISE407 LBA (1115 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 19.1 Lezgins__
2 19.6 Turkmens_Y
3 20.0 Tajiks_Y
4 20.7 Kumyks_Y
5 21.3 Zaza_P___
6 21.6 Turkish_Aydin_Ho
7 21.7 Turkish_Istanbul_Ho
8 22.0 Iranian_D
9 22.5 Kurd_D___
10 22.5 Kurds_Y___
Oracle K12B:
# Distance
1 9.0414 77.7% Lezgins__ + 22.3% Pais_Vasco_1KG
2 9.1657 70.8% Iranian_D + 29.2% Norwegian_D
3 9.4091 70.2% Kurd_D___ + 29.8% Swedish_D
4 9.4630 79.2% Lezgins__ + 20.8% French_Basque
5 9.5599 70.4% Kurd_D___ + 29.6% Norwegian_D
6 9.6359 70.1% Kurds_Y___ + 29.9% Swedish_D
7 9.6374 71.4% Lezgins__ + 28.6% Portuguese_D
8 9.6513 72.7% Lezgins__ + 27.3% Cataluna_1KG
9 9.6726 71.2% Lezgins__ + 28.8% Extremadura_1KG
10 9.6800 73.6% Lezgins__ + 26.4% Castilla_La_Mancha_1KG
Tuesday, February 24, 2015
Lactose intolerance: Six MCM6 variants in the Kurdish gene pool / Why 22018A is strongly, but not completely related to lactase persistence
In a previous post I
discussed the possibility of unknown MCM6 haplotypes in Middle Eastern
populations that could lead to lactose tolerance. I wrote:
Not all lactose tolerance SNPs are known, several SNPs resulting in lactose tolerance still need to be discovered.
Today, I want to present 6 haplotypes (ht1-6) I could discover in the Kurdish gene pool.
ht3 represents the "European" haplotype which correlates with lactose tolerance. Individuals with "CT" or "TT" at rs4988235 (also called C/T-13910) are genetically lactose tolerant; at 23andme it is "AG" or "AA" (because MCM6 gene is in minus orientation but 23andme does not address it).
Interestingly, 13910T (rs4988235: "A" at 23andme) and 22018A (rs182549: "T" at 23andme) are strongly linked with one another, at least for ht3, the "European" haplotype. However, this is not always the case. There is some literature about 22018A, see here, here, here, and here.
ht3 itself is derived from ht2, which only carries the 22018A mutation. ht2 is fairly rare and does not provide lactase persistence which explains why 22018A is strongly, but not completely related to lactase persistence.
The origin of the "European" lactose persistence 13910T (rs4988235: "A" at 23andme) can be found in populations where the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3).
In Kurds (N=20) the frequency of 22018A is 8% (ht2 + ht3), the frequency of 13910T is 5% (ht3). Both, ht2 and ht3 are derived from ht1, which has a frequency of 20% among Kurds.
Raz et al., 2013 found that Iraqi Jews (N=96) have a frequency 8.3% for 22018A (ht2 + ht3) and 3.6% for 13910T (ht3), which fits quite well with the Kurdish results.
Find below the frequency of the six MCM6 haplotypes in the Kurdish gene pool:
Find below the six haplotypes (ht1 - ht6) identified in the Kurdish gene pool (ht7 was identified in the Denisova genome. The coverage of the Neanderthal genome was too low to identify the haplotype.)
Find below the phylogenetic tree of MCM6 haplotypes.
Coehlo et al., 2005 predicted that 22018A mutation occured prior to the 13910T mutation.
Bersaglieri et al., 2004 provided the frequency of both 22018A and 13910T in various populations showing that the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3) in Pakistan (excluding Kalash).
Summary:
ht2 (22018A only) is the ancestor of ht3 (22018A + 13910T). ht2 can be found among Kurds, Iraqi Jews and Pakistanis.
I suspect that lactase persistence is also present among a subgroup of ht6.
Not all lactose tolerance SNPs are known, several SNPs resulting in lactose tolerance still need to be discovered.
Today, I want to present 6 haplotypes (ht1-6) I could discover in the Kurdish gene pool.
ht3 represents the "European" haplotype which correlates with lactose tolerance. Individuals with "CT" or "TT" at rs4988235 (also called C/T-13910) are genetically lactose tolerant; at 23andme it is "AG" or "AA" (because MCM6 gene is in minus orientation but 23andme does not address it).
Interestingly, 13910T (rs4988235: "A" at 23andme) and 22018A (rs182549: "T" at 23andme) are strongly linked with one another, at least for ht3, the "European" haplotype. However, this is not always the case. There is some literature about 22018A, see here, here, here, and here.
ht3 itself is derived from ht2, which only carries the 22018A mutation. ht2 is fairly rare and does not provide lactase persistence which explains why 22018A is strongly, but not completely related to lactase persistence.
The origin of the "European" lactose persistence 13910T (rs4988235: "A" at 23andme) can be found in populations where the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3).
In Kurds (N=20) the frequency of 22018A is 8% (ht2 + ht3), the frequency of 13910T is 5% (ht3). Both, ht2 and ht3 are derived from ht1, which has a frequency of 20% among Kurds.
Raz et al., 2013 found that Iraqi Jews (N=96) have a frequency 8.3% for 22018A (ht2 + ht3) and 3.6% for 13910T (ht3), which fits quite well with the Kurdish results.
Find below the frequency of the six MCM6 haplotypes in the Kurdish gene pool:
ht1 | ht2 | ht3 | ht4 | ht5 | ht6 |
20% | 3% | 5% | 15% | 10% | 48% |
Find below the six haplotypes (ht1 - ht6) identified in the Kurdish gene pool (ht7 was identified in the Denisova genome. The coverage of the Neanderthal genome was too low to identify the haplotype.)
SNP | ht1 | ht2 | ht3 | ht4 | ht5 | ht6 | ht7 |
rs4988283 | C | C | C | C | C | C | C |
rs4988262 | C | C | C | C | C | C | T |
rs2082730 | T | T | T | T | T | T | T |
rs4988243 | T | T | T | T | C | T | T |
rs4954492 | A | A | A | A | A | A | A |
rs41525747 | G | G | G | G | G | G | G |
rs4988236 | G | G | G | G | G | G | G |
rs4988235 | G | G | A | G | G | G | G |
rs41380347 | A | A | A | A | A | A | A |
rs4988234 | C | C | C | C | C | C | C |
rs4988233 | G | G | G | G | G | G | G |
rs2304369 | G | G | G | G | G | G | G |
rs4988232 | G | G | G | G | G | G | G |
rs4988226 | G | G | G | A | A | A | A |
rs309180 | A | A | A | G | G | G | G |
rs309181 | G | G | G | C | C | C | C |
rs3213871 | C | C | C | T | T | C | C |
rs4988203 | C | C | C | C | C | C | T |
rs182549 | C | T | T | C | C | C | C |
rs4988199 | A | A | A | A | A | A | A |
rs4988189 | T | T | T | T | T | T | T |
rs4988186 | G | G | G | G | G | G | G |
rs309176 | C | C | C | T | T | T | T |
rs3087343 | T | T | T | T | T | G | T |
rs4988177 | T | T | T | T | T | T | T |
rs3087353 | C | C | C | C | C | C | T |
rs2289049 | G | G | G | G | G | G | A |
rs2070068 | G | G | G | G | G | G | A |
rs1435577 | C | C | C | C | C | G | C |
rs3769001 | A | A | A | A | A | G | A |
rs1057031 | G | G | G | G | G | A | A |
Find below the phylogenetic tree of MCM6 haplotypes.
Coehlo et al., 2005 predicted that 22018A mutation occured prior to the 13910T mutation.
Bersaglieri et al., 2004 provided the frequency of both 22018A and 13910T in various populations showing that the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3) in Pakistan (excluding Kalash).
Summary:
ht2 (22018A only) is the ancestor of ht3 (22018A + 13910T). ht2 can be found among Kurds, Iraqi Jews and Pakistanis.
I suspect that lactase persistence is also present among a subgroup of ht6.
Thursday, January 15, 2015
Balaresque et al., 2015 (R1a)
Today, I want to identify R1a1 individuals that have the same STR8 haplotype (DYS393, DYS390, DYS19, DYS391, DYS439, DYS389i, DYS392, DYS389ii) as DS2 and DS15 in the recently published paper of Balaresque et al., 2015. Note that STR data have very limited information.
DS2 (perfect matches):
Dubai92 from Alshamali et al., 2009.
297613 Petr Sergeev Slyadnev, 1697, Oboyanskiy uezd R-CTS3402 (FTDNA)
230707 Philippe Renouf b 2/8/1730 Jersey R-Z284 (FTDNA)
349718 Iver Hansen Årholt, 1771, Stokke, VFL R-M512 (FTDNA)
M6619 R-Z93 (FTDNA)
243297 R-L657 (FTDNA)
163435 sayak 14с., kyrgyz R-M173 (FTDNA)
245562 R-M173 (probably Kyrgyz) (FTDNA)
220512 R-M173 (probably Kyrgyz) (FTDNA)
220490 R-M173 (probably Kyrgyz) (FTDNA)
220481 R-M173 (probably Kyrgyz) (FTDNA)
245558 R-M173 (probably Kyrgyz) (FTDNA)
249622 saribaghish (kyrgyz), KG R-M512 (FTDNA)
71094 Samuel Duncan, d.1679/80 MA R-M17 (FTDNA)
DS15 (perfect matches):
Qandahar/South Afghanistan (Sample Afg83) R1a1a* M198 from Lacau et al., 2012
Filipino (Sample431) from Hwa et al., 2010
Izeh [Bakhtiari] (Sample235) from Roewer et al., 2009
Nepal (Kathmandu) R1a1*-M17 (Sample NplK19) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK31) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK40) from Gayden et al., 2011
Nepal (Newar) R1a1*-M17 (Sample NplN67) from Gayden et al., 2011
N89389 Franz Gromann, b. about 1775 R-M512 (FTDNA)
N34838 Stephan Beres R-M198 (FTDNA)
256915 Mieczyslaw Seroka, Lublin province R-M417 (FTDNA)
200664 Simon Netke,abt 1686 -1735 R-M512 (FTDNA)
N47039 Otto Julius Madsen 1896 R-M417 (FTDNA)
264572 Franciscus Zloklikovits,b 1790 Eisenhuttl, Hungary R-CTS3402 (FTDNA)
127728 Andras Dutzman b. 1855 Levart Gemerska Slovakia R-M512 (FTDNA)
131773 Thomas Madon, Illinois? 1941? R-M512 (FTDNA)
N50210 Edmund Trawicki, geb. 1893, Legbad, Pomerania R-F2686 (FTDNA)
E13973 R-M512 (FTDNA)
191976 Mikita Kapustin, b. 1587, Novosil, Russia R-M417 (FTDNA)
257106 Lauri Heikinpoika Häyrinen, b. 1600, Joroinen R-M512 (FTDNA)
188784 Venedikt Vorotyntsev, b.ab.1660, N.Devitsa, Russia R-CTS456 (FTDNA)
283752 Yakim Loboda 1700 - 1750 R-M512 (FTDNA)
313105 Rönn R-Z92 (FTDNA)
201068 Porfyriy Skvortsov, ?-ca.1920, Radalivka, Ukraine R-Z92 (FTDNA)
140423 Olaf Andersson 1676-1759 Hemsjö Alingsås (O) R-M512 (FTDNA)
N23825 Jurgen Kolbe, b.c.1675, Angermunde, Brandenburg,Pr R-Z284 (FTDNA)
283402 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
283403 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
274445 Kete — Aidar — Azhibai — Seyit — Omar R-Z93 (FTDNA)
274482 Kete — Aidar — Azhibai — Seyit — Alkerey R-M512 (FTDNA)
192072 Adamyan, Aintab, Turkey R-Z93 (FTDNA)
N94836 Mr. İlyas Çiloğlu R-Z94 (FTDNA)
322561 Venkayya, b. 1830 R-M512 (FTDNA) 235474 R-M512 (FTDNA)
235471 R-M512 (FTDNA)
M8466 R-CTS3402 (FTDNA) M8458 R-PAGES00007 (FTDNA)
186386 need earliest known paternal ancestor info R-M198 (FTDNA)
245563 R-M512 (FTDNA)
336409 Solto-Tœlœk R-M512 (FTDNA) 219713 Sayak ~14c R-M512 (FTDNA)
277359 Malkarov, Balkaria (Chegem→Baskhan) R-F1345 (FTDNA)
221211 R-M512 (FTDNA) 20409 Gerd Bonorden born about 1500 Bielfel Germany R-M512 (FTDNA)
295213 John T. Windsor, b. 1839 (IN), d. 1924 (MO) R-Z94 (FTDNA)
M8568 R-M512 (FTDNA)
N3798 Raghavendra Kamath 1913-1989 Karkal India R-Z94 (FTDNA)
306446 Aslan Hadji,gf of İ.Akbaev,Chokuna Efendi,Karachay R-M512 (FTDNA)
237819 Abraham Kennedy, b. 1858, Vilnius; d. U.S./Poland R-M512 (FTDNA)
255385 Samuel Duncan, b 1619 and d April 1680 R-M512 (FTDNA)
188766 R-M198 (FTDNA) 177329 R-M512 (FTDNA)
N112185 Ayyapankave Ramakrishna Krishmamurthy, b1926, Ayya R-M512 (FTDNA)
306019 ataul Tiyrnakla, Bayramuk, Karachay R-M512 (FTDNA)
336372 R-M512 (FTDNA)
N87639 Lemuel Murry,1826 -1909 Milton, Rutherford Co.TN R-M17 (FTDNA)
120827 Samuel Irvine, 1789, Limavady, County Londonderry R-M512 (FTDNA)
208262 Fernando Domingo Gutierrez, b. abt 1825 R-M512 (FTDNA)
Edit 01/16.2015:
I started to read the paper. In the supplementary table 3 it provides the number of individuals of each region belonging to a specific DC. I focused on Cinnioglu et al., 2004 data that is included in the supplementary table 3. It claims that in East Anatolia (region 4) 9 out 82 belong to DC2. There are only 9 individuals in region 4, none of them is a perfect match. I realized that only 5 out of 8 STRs need to be identical to belong to DC2 (this is a pretty vague cluster). Using this vague rule I identified more than 800 individuals that are within cluster DC2, a lot of them are not within Z93 and from Europe (Z282+ individuals):
https://docs.google.com/spreadsheets/d/1V5Wumf-nP5NNn1Y57GTxuAw2_cU2XA5pqe4MWzT6Dpo/edit?usp=sharing
Overall, this suggests that data using STR values have very little value, no matter where it is published, especially when it is about vague clusters based on 8 STRs only.
Edit2 01/16.2015:
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 1792 out of 3418 belonging to DC2 (52.4%).
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 2668 out of 3418 belonging to DC15 (78.1%).
This highlights that STR values cannot substitute SNPs.
DS2 (perfect matches):
Dubai92 from Alshamali et al., 2009.
297613 Petr Sergeev Slyadnev, 1697, Oboyanskiy uezd R-CTS3402 (FTDNA)
230707 Philippe Renouf b 2/8/1730 Jersey R-Z284 (FTDNA)
349718 Iver Hansen Årholt, 1771, Stokke, VFL R-M512 (FTDNA)
M6619 R-Z93 (FTDNA)
243297 R-L657 (FTDNA)
163435 sayak 14с., kyrgyz R-M173 (FTDNA)
245562 R-M173 (probably Kyrgyz) (FTDNA)
220512 R-M173 (probably Kyrgyz) (FTDNA)
220490 R-M173 (probably Kyrgyz) (FTDNA)
220481 R-M173 (probably Kyrgyz) (FTDNA)
245558 R-M173 (probably Kyrgyz) (FTDNA)
249622 saribaghish (kyrgyz), KG R-M512 (FTDNA)
71094 Samuel Duncan, d.1679/80 MA R-M17 (FTDNA)
DS15 (perfect matches):
Qandahar/South Afghanistan (Sample Afg83) R1a1a* M198 from Lacau et al., 2012
Filipino (Sample431) from Hwa et al., 2010
Izeh [Bakhtiari] (Sample235) from Roewer et al., 2009
Nepal (Kathmandu) R1a1*-M17 (Sample NplK19) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK31) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK40) from Gayden et al., 2011
Nepal (Newar) R1a1*-M17 (Sample NplN67) from Gayden et al., 2011
N89389 Franz Gromann, b. about 1775 R-M512 (FTDNA)
N34838 Stephan Beres R-M198 (FTDNA)
256915 Mieczyslaw Seroka, Lublin province R-M417 (FTDNA)
200664 Simon Netke,abt 1686 -1735 R-M512 (FTDNA)
N47039 Otto Julius Madsen 1896 R-M417 (FTDNA)
264572 Franciscus Zloklikovits,b 1790 Eisenhuttl, Hungary R-CTS3402 (FTDNA)
127728 Andras Dutzman b. 1855 Levart Gemerska Slovakia R-M512 (FTDNA)
131773 Thomas Madon, Illinois? 1941? R-M512 (FTDNA)
N50210 Edmund Trawicki, geb. 1893, Legbad, Pomerania R-F2686 (FTDNA)
E13973 R-M512 (FTDNA)
191976 Mikita Kapustin, b. 1587, Novosil, Russia R-M417 (FTDNA)
257106 Lauri Heikinpoika Häyrinen, b. 1600, Joroinen R-M512 (FTDNA)
188784 Venedikt Vorotyntsev, b.ab.1660, N.Devitsa, Russia R-CTS456 (FTDNA)
283752 Yakim Loboda 1700 - 1750 R-M512 (FTDNA)
313105 Rönn R-Z92 (FTDNA)
201068 Porfyriy Skvortsov, ?-ca.1920, Radalivka, Ukraine R-Z92 (FTDNA)
140423 Olaf Andersson 1676-1759 Hemsjö Alingsås (O) R-M512 (FTDNA)
N23825 Jurgen Kolbe, b.c.1675, Angermunde, Brandenburg,Pr R-Z284 (FTDNA)
283402 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
283403 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
274445 Kete — Aidar — Azhibai — Seyit — Omar R-Z93 (FTDNA)
274482 Kete — Aidar — Azhibai — Seyit — Alkerey R-M512 (FTDNA)
192072 Adamyan, Aintab, Turkey R-Z93 (FTDNA)
N94836 Mr. İlyas Çiloğlu R-Z94 (FTDNA)
322561 Venkayya, b. 1830 R-M512 (FTDNA) 235474 R-M512 (FTDNA)
235471 R-M512 (FTDNA)
M8466 R-CTS3402 (FTDNA) M8458 R-PAGES00007 (FTDNA)
186386 need earliest known paternal ancestor info R-M198 (FTDNA)
245563 R-M512 (FTDNA)
336409 Solto-Tœlœk R-M512 (FTDNA) 219713 Sayak ~14c R-M512 (FTDNA)
277359 Malkarov, Balkaria (Chegem→Baskhan) R-F1345 (FTDNA)
221211 R-M512 (FTDNA) 20409 Gerd Bonorden born about 1500 Bielfel Germany R-M512 (FTDNA)
295213 John T. Windsor, b. 1839 (IN), d. 1924 (MO) R-Z94 (FTDNA)
M8568 R-M512 (FTDNA)
N3798 Raghavendra Kamath 1913-1989 Karkal India R-Z94 (FTDNA)
306446 Aslan Hadji,gf of İ.Akbaev,Chokuna Efendi,Karachay R-M512 (FTDNA)
237819 Abraham Kennedy, b. 1858, Vilnius; d. U.S./Poland R-M512 (FTDNA)
255385 Samuel Duncan, b 1619 and d April 1680 R-M512 (FTDNA)
188766 R-M198 (FTDNA) 177329 R-M512 (FTDNA)
N112185 Ayyapankave Ramakrishna Krishmamurthy, b1926, Ayya R-M512 (FTDNA)
306019 ataul Tiyrnakla, Bayramuk, Karachay R-M512 (FTDNA)
336372 R-M512 (FTDNA)
N87639 Lemuel Murry,1826 -1909 Milton, Rutherford Co.TN R-M17 (FTDNA)
120827 Samuel Irvine, 1789, Limavady, County Londonderry R-M512 (FTDNA)
208262 Fernando Domingo Gutierrez, b. abt 1825 R-M512 (FTDNA)
Edit 01/16.2015:
I started to read the paper. In the supplementary table 3 it provides the number of individuals of each region belonging to a specific DC. I focused on Cinnioglu et al., 2004 data that is included in the supplementary table 3. It claims that in East Anatolia (region 4) 9 out 82 belong to DC2. There are only 9 individuals in region 4, none of them is a perfect match. I realized that only 5 out of 8 STRs need to be identical to belong to DC2 (this is a pretty vague cluster). Using this vague rule I identified more than 800 individuals that are within cluster DC2, a lot of them are not within Z93 and from Europe (Z282+ individuals):
https://docs.google.com/spreadsheets/d/1V5Wumf-nP5NNn1Y57GTxuAw2_cU2XA5pqe4MWzT6Dpo/edit?usp=sharing
Overall, this suggests that data using STR values have very little value, no matter where it is published, especially when it is about vague clusters based on 8 STRs only.
Edit2 01/16.2015:
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 1792 out of 3418 belonging to DC2 (52.4%).
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 2668 out of 3418 belonging to DC15 (78.1%).
This highlights that STR values cannot substitute SNPs.
Wednesday, October 22, 2014
Kurdish mtDNA data XII
Just an update (N=207):
Related post:
mtDNA of Kurds Part I
mtDNA of Kurds Part II
mtDNA of Kurds Part III
mtDNA of Kurds Part IV
mtDNA of Kurds V
Kurdish mtDNA data VI
Kurdish mtDNA data VII
Kurdish mtDNA data VIII
Kurdish mtDNA data IX
Kurdish mtDNA data X
Kurdish mtDNA data XI
1x B4b1a (Kurd from
Turkey)
1x C (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x C4b (=C4b+A248G, A14566G,
T16519C, A249A (not deleted)) (Alevi Kurmanji)
1x C5c1 (C5c1b based on
Derenko et al, 2013; mtDNA fully sequenced: KC911629) A249DEL, T3552A, A9545G, G11914A, A13263G, T14318C, C16327T, 595.1C, T16288C,
T10454C, G16518T, C16527T, C16234T, 315.1C, G7521A, C9431A, T11465C, T16519C
(Kurd from Baneh/Iran; Derenko et al., 2013)
2x D (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x D4 T16090C/T, T16223C,
T16362C, A73G, A263G, 309.1C, 315.1C (Kurds from Iran; Derenko et al., 2007)
2x D4 T16223C, T16362C,
A73G, A263G, 309.1C, 315.1C (Kurds from Iran; Derenko et al., 2007
1x F1b1 (F1b1* based on
Derenko et al, 2013; mtDNA fully sequenced: KC911336) T152C, C10976T, C12633T, G14476A, T16189C,
C16232A, T16249C 16311C, T204C, 309.1C, 315.1C, 523DEL, 524DEL, C3533T, A8718G, G13759A, 15398G, A16183C, T16519C (Kurd from
Kermanshah/Iran; Derenko et al., 2013)
1x G2a (=G2a+T16172C)
(Sorani)
8x H (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x H CRS (Kurds from Iran;
Quintana-Murci et al., 2004)
6x H (Kurds from Georgia;
Comas et al., 2000)
2x H with T16311C
(Kurds from Georgia; Comas et al., 2000)
1x H T16209C, 44.1C, T57C,
A93G, A263G, 309.1C, 309.2C, 315.1C (Kurds from Iran; Derenko et al., 2007)
1x H G16129A, C16248T,
T195C, A263G, 315.1C (Kurds from Iran; Derenko et al., 2007)
1x H CRS, A263G, 315.1C
(Kurds from Iran; Derenko et al., 2007)
1x H with C16218T (=H1ag1a
or H1aq1 or H20) (Kurds from Georgia; Comas et al., 2000)
1x H with C16192R, C16261T
(similar to: JN415470(Italy-LHON) Achilli Haplogroup H 19-AUG-2012 (Kurds from
Georgia; Comas et al., 2000)
1x H1 (Kurd from Dersim)
1x H5'36 (Kurd from Turkey)
1x H5 16051G, 16255A,
16304C, 16319A, 16327T, 263G, 315.1C, 456T (Kurds from Iraq; Al-Zahery et al.,
2012)
1x H5a1 (H5a1+T16304G,
A3397G, G5471A) (G5471A usually in H5b) (Sorani)
1x H13a2b2 (Alevi Kurmanji
from Dersim)
1x H13c (H13c2 based on
Derenko et al, 2013; mtDNA fully sequenced: KC911276) G143A, A153G, 309.1C, 309.2C, 315.1C, 523DEL,
524DEL, 15406T, G16129A, A16300G (Kurd
from Kermanshah/Iran; Derenko et al., 2013)
1x H13c1 (H13c1+T3398C,
T10463C, T15394C) (Alevi Kurmanji from Sivas and Erzincan)
1x H14a with T16311C,
C16256T, T16352C (=H14a +T16311C ) (Kurds from Georgia; Comas et al., 2000)
1x H14b T3197C
(=H14b+C4086T, A16265T) (Yezidi)
1x H15b (Sorani)
1x H15b T16086C (close to
EU600353(Druze) Shlush)(Kurds from Iran; Quintana-Murci et al., 2004)
1x H20 (3/4 Zaza from
Bingol, 1/4 (paternal grandmother) Kurmanji from Bitlis)
5x HV (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x HV* CRS (Kurds from Iran;
Quintana-Murci et al., 2004)
1x HV* C16174T (Kurds from
Iran; Quintana-Murci et al., 2004)
1x HV C16174T, C41T, A214G,
A263G, 309.1C, 309.2C, 315.1C (Kurds from Iran; Derenko et al., 2007)
1x HV A73G, T391C, G16153A
(Kurmanji from Zakho)
1x HV1 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x HV1a1 C16067T, C16355T,
C150T, A263G, 315.1C (Kurds from Iran; Derenko et al., 2007)
1x HV1a1 C16067T, C16355T
(=HV1a1) (Kurds from Iran; Quintana-Murci et al., 2004)
1x HV1b2 (HV1b2+T3398C G13368A,
T16519C)(Yezidi Kurd from Georgia)
1x HV2 C16168T, T16189C,
T16217C, C16287T (Kurds from Iran; Quintana-Murci et al., 2004)
1x HV2a1 (T246C, C16214T,
A16335G (=HV2a1) additional G13708A (Kurmanji Sunni from
Sirnak/Hasankeyf/Nisebin/Mardin/Kamishli)
1x HV14 (T480C, G4655A,
T15115C =HV14) (Kurmanji from Diyarbakir (Amed)/Turkey)
1x HV14 T16311C, G4655A,
T15115C (Sorani from Koysinjaq)
1x I (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x I with G16129A, C16223T
(Kurds from Georgia; Comas et al., 2000)
1x I1 (I based on Fernandes
et al, 2012; mtDNA fully sequenced: JQ245776) T250C, A4529T, G8251A A15924G, G16391A, T10034C, G16129A, 455.1T, G6734A, G9966A,
T16311C, 291.1A, 294.1T, 309.1C, 315.1C, 2244C, T7705C, T14757C, T16519C (Kurd from Turkey;
Fernandes et al, 2012)
1x I1a G16129A, C16168T,
T16172C, 16173, C16223T (Kurds from Iran; Quintana-Murci et al., 2004)
1x I1a1d with G16129A,
C16223T, T16172C, T16189C, C16083T, C16355T (=I1a1d+C16083T, C16355T) (Kurds
from Georgia; Comas et al., 2000)
1x I5a (Kurd from Turkey)
1x I5a pre-I5a3
because G5231A, A15052G = I5a3 but still C150C, T6278T = I5a; additional
C16301T (Zaza from Dersim)
1x I5a (Zaza from
Baltas/Varto, Turkey)
1x J* (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
2x J1b (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x J1b C16069T, T16126C,
G16145A, C16222T, A16235G, C16261T, T16311C (Kurds from Iran; Quintana-Murci et
al., 2004)
1x J1b1b1 T10410A, C16069T,
T16126C, G16145A, C16261T, C16290T, A73G, A263G, C271T, C295T, 309.1C, 315.1C
(Kurds from Iran; Derenko et al., 2007)
2x J1b1b1 T10410A, C16069T,
T16126C, G16145A, C16261T, A73G, A263G, C295T, 309.1C, 315.1C (Kurds from Iran;
Derenko et al., 2007)
2x J1b1b1 C16069T, T16126C,
G16145A, C16261T, T16519C, A73G, A263G, C295T, 309.1C 315.1C,
C462T, T489C, 523DEL, 524DEL (very close to JF939049(Armenian))
(Kurds from Iraq; Al-Zahery et al., 2012)
3x J1b2 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x J1b3 (Kurd from Turkey)
1x J1b3 T1822C, A8460G,
A16235A, T16311C (=J1b3+T1822C+T16311C) (Sorani)
1x J1b3b A73G, A263G, C295T,
T489C, A750G, A1438G, A2706G, G3010A, T4216C, A4769G, C7028T, G8269A, A8460G,
A8860G, A10398G, A11251G, G11719A, A12612G, G13708A, C14766T, A15326G, C15452A,
T15530C, C16069T, T16126C, G16145A, C16222T, A16235G, C16261T (1/2 Alevi
Kurmanji paternally, 1/2 Sunni Kurmanji maternally from Bingol, Kighi, Turkey)
1x J1b3b ( Kurd from Dersim)
1x J1b4 C16069T, T16126C,
G16145A, C16222T, C16261T, C16278T, C16287T (Kurds from Iran;
Quintana-Murci et al., 2004)
1x J1c (=J1c+G185T, 4812A,
C16290T, T16519C) (Alevi Kurmanji from Dersim)
1x J1c2m (old J1c2a)
C16069T, T16126C, 16148T, A73G, 185A, 228A, A263G, C295T, 315.1C, C462T, T489C,
523DEL, 524DEL (close to JQ797801 from Romania and JQ797802 from
West-Siberia (Khanty))(Kurds from Iraq; Al-Zahery et al., 2012)
1x J1d (=J1d+A15218G,
T16519C) (Feyli, originally from Iran)
1x J1d (Kurd from Iraq)
1x J1d3b (=J1d3b+10742G,
T11353C, 12425G, T16519C (Kurmanji Alevi from Adıyaman and Gaziantep; now
living in Konya area)
1x J2a1a1 C16069T, T16126C,
G16145A, A16182C, A16183C, T16189C, 16193.1C, T16231C, C16261T, A73G, C150T,
C152T, T195C, C198T, A215G, C295T, 315.1C, T319C (Kurds from Iran; Derenko et
al., 2007
1x J2a1a1 (=J2a1a1+A10044G,
G11914A, C16264T) (Kurd from Turkey)
3x J2b (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x J2b1 (Kurd from
Iraq/Iran)
1x J2d C16069T, T16126C,
C16193T, A73G, C152T, A263G, C295T, 315.1C (Kurds from Iran; Derenko et al.,
2007)
1x JT with T16126C, C16067T,
T16311C (=JT) (Kurds from Georgia; Comas et al., 2000)
1x K (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x K 16129, T16224C, T16311C
(= K1a11 or K2b2) (Kurds from Iran; Quintana-Murci et al., 2004)
1x K with T16224C, T16311C
(Kurds from Georgia; Comas et al., 2000)
2x K with T16224C, T16311C,
T16093C, C16260T (=K1a1+C16260T, or K1a17a+T16093C)(Kurds from Georgia; Comas
et al., 2000)
1x K with T16224C, T16311C,
A16240G (=K+A16240G) (Kurds from Georgia; Comas et al., 2000)
1x K with T16224C, T16311C,
A16272G (=K+A16272G) (Kurds from Georgia; Comas et al., 2000)
1x K1a T16093C, T16224C,
T16311C (Kurds from Iran; Quintana-Murci et al., 2004)
1x K1a9 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x K1b1c (K1b1c based on
Derenko et al, 2013; mtDNA fully sequenced: KC911572) T1189C, A10398G, G5913A, G9962A, A10289G, C15946T, G94A, G3337A, G11914A,
309.1C, 315.1C, T650C, A5811G, G8545A, T16519C (Kurd from Mashhad/Iran; Derenko et al.,
2013)
1x L3e5 16037G, A16041G,
C16223T, A73G, C150T, A263G, 315.1C, T398C, 523DEL, 524DEL (Kurds from Iraq;
Al-Zahery et al., 2012)
1x M/C (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x M1a1 G16129A, 16182C,
16183C, T16189C, C16223T, T16249C, T16311C, T16359C, C16360T, T16519C, A73G,
T195C, A263G, 309.1C, 309.2C, 315.1C, T489C (Kurds from Iraq; Al-Zahery et al.,
2012)
5x N (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x N1b (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x N1b1 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x N1b1 (=N1b1+C16176C,
C1703A, C3921A, G7337A, T16519C) (Alevi Kurmanji from Dersim)
1x N1b1 with C16223T,
G16145A, C16176G (=N1b1) (Kurds from Georgia; Comas et al., 2000)
1x N1b1a6 (N1b based on
Fernandes et al, 2012; mtDNA fully sequenced: JQ245756) C1703T, C3921A, C4960T, C8472T, A12822G, G16145A, C9335C, A11362G, C7010T,
T8469C, 309.1C, 315.1C, 523DEL, 524DEL,
G7337A, G9133A, A14690G (Kurd from Turkey; Fernandes et al, 2012)
1x N2a with C16223T,
T16086C, G16153A, G16319A (=N2a+T16086C) (Kurds from Georgia; Comas et al.,
2000)
1x R (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
2x R0 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x R0 16519C, 16524C, A263G,
315.1C (Kurds from Iraq; Al-Zahery et al., 2012)
1x R0 16368C, 16519C, A263G,
309.1C, 315.1C (Kurds from Iraq; Al-Zahery et al., 2012)
1x R2 with C16071T, G16145A,
C16234 (=R2 +G16145A+C16234) (Kurds from Georgia; Comas et al., 2000)
1x T* T16126C, T16189C,
16193.1C, T16249C, C16294T, T16304C, A73G, T146C, T195C, A263G, 309.1C, 315.1C
(Kurds from Iran; Derenko et al., 2007)
1x T1a1'3 T16126C, A16163G,
C16186T, T16189C, C16294T, A73G, T152C, T195C, A263G, 315.1C (Kurds from Iran;
Derenko et al., 2007)
4x T1 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x T1a2b (=T1a2b+C12633T,
G5460A, G11914A, T16311C, (T16519C))(Feyli)
1x T1 (Alevi Kurmanji from
Dersim)
1x T1 (Kurd from Baneh/Iran)
1x T1a7 T16126C, A16163G,
C16186T, T16189C, G16274A, C16294T, T16519C, A73G, A263G, 309.1C, 315.1C,
A512G (close to EU935435(Egypt) Kujanova and JQ798027 (Israel))(Kurds
from Iraq; Al-Zahery et al., 2012)
1x T1b T16126C, A16163G,
T16189C, T16243C, C16294T, A73G, A263G, 309.1C, 315.1C (Kurds from Iran;
Derenko et al., 2007)
1x T1b T16126C, A16163G,
T16189C, T16243C, A16247G, C16294T, T16519C, A73G, 152C, A263G, 309.1C, 315.1C,
524.1A, 524.2C (Kurds from Iraq; Al-Zahery et al., 2012)
3x T2 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x T2a1b2b with T16126C,
C16294T, C16296T, C16256T, A16317G (=T2a1b2b +A16317G) (Kurds from Georgia;
Comas et al., 2000)
1x T2b (Kurd from Turkey)
1x T2c1 (Kurd from Iran,
originally from Amed)
1x U1a'c A16182C, A16183C,
T16189C, T16249C, A73G, T146C, A263G, C285T, 309.1C (similar to
HM852844(Iranian 9) Schoenberg) (Kurds from Iran; Derenko et al., 2007)
1x U1a'c with A16182C,
A16183C, T16189C, T16249C (=U1a'c) (Kurds from Georgia; Comas et al., 2000)
1x U1a (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x U1a1 A14070A, T16163C
(Zaza)
1x U1a1 G16129A, A16183C,
T16189C, 16193.1C, T16224C, T16249C, T16288C, C16295T, A73G, C150T, T195C,
A263G, C285T, 309.1C, 309.2C, 315.1C, A385G (Kurds from Iran; Derenko et al.,
2007)
1x U1a1 A16183-, 16193.1C,
C16193T.2C, T16249C, T72C, A73G, T195C, A263G, C285T, 309.1C, 315.1C, A385G
(Kurds from Iran; Derenko et al., 2007)
1x U1a1a (Sorani) with
A11467G, A12308G, G12372A, C285T, T12879C, A13104G,
A14070G, G15148A, A15954C, T16249C, C2218T, G14364A, T16189C, G4991A, G6026A,
T7581C, A385G, 3158.1T, G3591A, A13422G, G9575A, C2836T, G4659A, 573.1C,
573.2C, A10283G, (309.1C), (315.1C), (523-), (524-), (16182C), (16183C),
(16519C) (=U1a1a; shares C2836T, G4659A mutation with Indian samples
HM156682(India) Govindaraj) (fully sequenced here and here)
1x U1b C16111T, 16214A,
T16249C, G16319A, C16327T, T16519C, A73G, T146C, T152C, A263G, C285T, 315.1C,
572T (Kurds from Iraq; Al-Zahery et al., 2012)
1x U2 (Alevi with Zaza ancestry)
1x U2e1a with A16051G,
T152C, A508G, A3720G, A5390G, T5426C, C6045T, T6152C, A10876, T13020C, T13734C,
A15907G, G16129C, T16362C, C340T, C11197T, T11732C, G7337A, A15218G, T16311C,
T16519C (Sorani from Sulaymaniyah/Iraq)
1x U3 with A16343G (=U3)
(Kurds from Georgia; Comas et al., 2000)
1x U3a (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x U3a with C150T,
A14139G, T15454C, A2294G, T4703C, G9266A, T6518A
(flip!), A10506G, C13934T,
G16390A, C2766A, 10790C, G16129A, 16257T, T16519C (Sorani from
Sulaymaniyah/Iraq); (similar to HM852895(Georgian45) Schoenberg also with
C2766A)
1x U3b with (U3b+G3591A,
C15946T, A16203G, T16311C, T16356C, C4640T (flip!) (Kurmanji Sunni from
Hakkari/Mardin)
1x U3c with A16343G,
C16193T, T16249C (=U3c) (Kurds from Georgia; Comas et al., 2000)
1x U3c C16193T, T16249C,
A16343G, G16526A, A73G, C150T, A263G, 315.1C (close to HM852797(Azeri34)
and HM852803(Azeri42) Schoenberg)(Kurds from Iraq; Al-Zahery et al.,
2012)
1x U4 T16356C, T16519C,
A73G, T195C, A263G, 309.1C, 315.1C, G499A, 524.1A, 524.2C (Kurds from Iraq;
Al-Zahery et al., 2012)
1x U5 T16093C, T16189C,
C16270T (Kurds from Iran; Quintana-Murci et al., 2004)
1x U5a1 (Kurmanji from
Dohuk)
1x U5a1a (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x U5a1a1 (Sorani,
maternally Kurdish from Ardalan)
4x U7 (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x U7 (Zaza from Turkey)
1x U7 (Zaza from Dersim)
1x U7 (Kurd from Rojhelat,
Iran; paternally from Kalakajar outside Tikab and maternally from Sine)
1x U7 C16069T, A16227G,
C16278T, A16318C, T16359C (very close to HM852853(Turk 187) Schoenberg) (Kurds
from Iran; Quintana-Murci et al., 2004)
1x U7 C16192T, A16309G,
A16318T (Kurds from Iran; Quintana-Murci et al., 2004)
1x U7 T16243C, A16309G,
A16318T (Kurds from Iran; Quintana-Murci et al., 2004)
1x U7 A16309G, A16318T
(Kurds from Iran; Quintana-Murci et al., 2004)
1x U7 A16309G, A16318T
(Kurds from Georgia; Comas et al., 2000)
1x U7a A16309G, A16318T,
T16519C, A73G, C151T, T152C, A263G, 309.1C, 315.1C, 523DEL, 524DEL (Kurds from
Iraq; Al-Zahery et al., 2012)
1x U7a2 (U7a2a1 based on
Derenko et al, 2013; mtDNA fully sequenced: KC911509) A16318T, T16519C, A73G, C151T, T152C, A263G,
315.1C, 523DEL, 524DEL, A5265G, T7870C, C12094T, C14533T, G16129A, A16309A,
T16519C (Kurd from Kermanshah/Iran;
Derenko et al., 2013)
1x U7a4 T16126C, C16148T,
A16309G, A16318T, A73G, T146C, C150T, C152T, T195C, A263G, 315.1C (Kurds from
Iran; Derenko et al., 2007)
1x U7a4 T16126C, C16148T,
A16318C, A73G, T146C, C151T, C152T, T195C, A263G, 315.1C (Kurds from Iran;
Derenko et al., 2007)
1x U7a4 T16126C, C16148T,
A16318T, A73G, T146C, C151T, C152T, T195C, A263G, 309.1C, 315.1C (Kurds from
Iran; Derenko et al., 2007)
1x U7a'5 G16129A, A16318T,
A73G, C151T, C152T, A263G, 309.1C, 315.1C (Kurds from Iran; Derenko et al.,
2007)
1x U8b1a1 A16066G, G16129A,
A16183C, T16189C, C16234T, A73G, G94A, T195C, A263G, 309.1C, 309.2C, 315.1C
(Kurds from Iran; Derenko et al., 2007)
1x U8b1a1 A16066G, G16129A,
C16169T, A16183C, T16189C, C16234T, T16311C (Kurds from Iran; Quintana-Murci et
al., 2004)
1x U8b C16111T, T16172C,
A16183C, T16189C, T16311C (Kurds from Iran; Quintana-Murci et al., 2004)
1x U8b (Feyli)
1x U8b (Zaza from Sivas,
originally from Dersim)
1x W (Kurds from Saqqez,
Kurdistan-Iran; Farjadian et al., 2011)
1x W C16223T, C16292T (Kurds
from Iran; Quintana-Murci et al., 2004)
1x W3 G16153A, C16223T,
C16292T, C16294T, T16519C, A73G, T152C, A189G, C194T, T195C, T199C, T204C,
G207A, A263G, 309.1C, 315.1C (Kurds from Iraq; Al-Zahery et al., 2012)
1x W3a1 (W based on
Fernandes et al, 2012; mtDNA fully sequenced: JQ245760) T195C, T204C, G207A, T1243C, A3505G, G5460A, G8251A, G8994A, A11947G, G15884C,
C16292T, C194T, T1406C, T15784C, A13263G,
309.1C, 315.1C, G1709A, C10845T, G16244A, T16368C, T16519C (Kurd from Turkey; Fernandes et al, 2012)
1x W3b (W based on Fernandes
et al, 2012; mtDNA fully sequenced: JQ245757) T195C, T204C, G207A, T1243C, A3505G, G5460A, G8251A G8994A, A11947G, G15884C,
C16292T, C194T, T1406C, T199C, G12923T,
315.1C, T1413C, C1693T, A2258G, G8950A, C11467G, C12063T, C14557T,
T14634C, T16519C (Kurd from Turkey;
Fernandes et al, 2012)
1x W3b (Olivieri et al, 2013; mtDNA fully sequenced:
KF146279) T195C, T204C, G207A, T1243C, A3505G, G5460A, G8251A, G8994A, A11947G, G15884C, C16292T,
C194T, T1406C, T199C, G12923T, 315.1C,
T4216C, T16519C (Kurdistan, Iran; Olivieri et al, 2013)
1x W4a C16223T, C16292T,
C16286T (Kurds from Iran; Quintana-Murci et al., 2004)
1x W4d (W based on Fernandes
et al, 2012; mtDNA fully sequenced: JQ245758) T195C, T204C, G207G, T1243C, A3505G, G5460A, G8251A, G8994A, A11947G, G15884C,
C16292T, C194T, G143A, T196C, C16286C,
C16082T, T119C, T146C, 309.1C, 315.1C, 523DEL, 524DEL, A6977G, C13011T,
G13145A, A15308G, T16519C (Kurd from
Turkey; Fernandes et al, 2012)
1x W6 with C16292T, C16192T,
C16223T, T16324C (=W6) (Kurds from Georgia; Comas et al., 2000)
1x W6c with A73G, A189G,
C194T, T195C, T204C, G207A, A263G, 309.1C, 315.1C, C16211T, C16223T, C16292T,
T16325C, T16519C (N91920 Kurdish Gule, ≈1850,
Ahlat/Kurdistan-Turkey)
1x W6c1a (mtDNA fully sequenced: KF553923) T195C,
T204C, G207G, T1243C, A3505G, G5460A, G8251A, G8994A, A11947G, G15884C, C16292T, C194T, A4093G,
T8614C, T16325C, C8002T, C8658T, A8149G,
C16211T, 309.1C, 315.1C, C8874T, T16519C (Kurd from Tatvan near Lake
Van)
1x W9 (W based on Fernandes
et al, 2012; mtDNA fully sequenced: JQ245759) T195C, T204C, G207G, T1243C, A3505G, G5460A, G8251A, G8994A, A11947G, G15884C,
C16292T, C194T, C14097T, 309.1C, 315.1C,
523DEL, 524DEL, A5128G, G16129A, T16519C (Kurd from Turkey; Fernandes et
al, 2012)
1x X with T16189C, C16278T,
C16186T (=X+C16186T) (Kurds from Georgia; Comas et al., 2000)
1x X2e T16124C, A16182C,
A16183C, T16189C, 16193.1C, T16223C, C16278T, T16325C, A73G, A153G, T195C,
A263G, 308.1A, 309.1C, 315.1C, C338T (Kurds from Iran; Derenko et al., 2007)
mtDNA of Kurds Part I
mtDNA of Kurds Part II
mtDNA of Kurds Part III
mtDNA of Kurds Part IV
mtDNA of Kurds V
Kurdish mtDNA data VI
Kurdish mtDNA data VII
Kurdish mtDNA data VIII
Kurdish mtDNA data IX
Kurdish mtDNA data X
Kurdish mtDNA data XI
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