Full mtDNA sequence of haplogroup U1a1

Today, I want to present the latest results of haplogroup U1a1. Haplogroup U1a1 got my attention a while ago, since we have already three Kurdish individuals with U1a1 I thought to give it another post.

Kurds with U1a1:
1x U1a1 (Zaza)
1x U1a1 (Sorani)
1x U1a1 with A16182C, A16183C, T16189C, T16249C (=U1a1) (Kurds from Georgia; Comas et al., 2000)

For the first time, we have the full mtDNA sequence of a Kurd (Sorani) with U1a1.


Of course, I compared the data of this Kurdish individual with other complete U1a1 mtDNA sequences. It turns out that he has the G9575A mutation, so he belongs to U1a1a.

Based on mtDNA haplogroup predictor his mtDNA turned out to be haplogroup U1a1a.

Best mtDNA Haplogroup Matches:
1) U1a1a
Defining Markers for haplogroup U1a1a:
HVR2: 73G 263G 285T 385G
CR: 750G 1438G 2218T 2706G 3158.1T 3591A 4769G 4991A 6026A 7028T 7581C 8860G 9575A 11467G 11719A 12308G 12372A 12879C 13104G 13422G 14070G 14364A 14766T 15148A 15326G 15954C
HVR1: 16189C 16249C
Marker path from rCRS to haplogroup U1a1a (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 14766T ⇨ R0 ⇨ 73G 11719A ⇨ R ⇨ 11467G 12308G 12372A ⇨ U ⇨ 285T 12879C 13104G 14070G 15148A 15954C 16249C ⇨ U1 ⇨ 2218T 14364A 16189C ⇨ U1a'c ⇨ 4991A 6026A 7581C ⇨ U1a ⇨ 385G 3158.1T 3591A 13422G ⇨ U1a1 ⇨ 9575A ⇨ U1a1a ⇨ (309.1C) (315.1C) (523-) (524-) 573.1C 573.2C 2836T 4659A 10283G (16182C) (16183C) (16519C)
Good Match! Your results also had extra markers for this haplogroup:
Matches(32): 73G 263G 285T 385G 750G 1438G 2218T 2706G 3158.1T 3591A 4769G 4991A 6026A 7028T 7581C 8860G 9575A 11467G 11719A 12308G 12372A 12879C 13104G 13422G 14070G 14364A 14766T 15148A 15326G 15954C 16189C 16249C
Extras(5): (309.1C) (315.1C) (523-) (524-) 573.1C 573.2C 2836T 4659A 10283G (16182C) (16183C) (16519C)


Compared to other U1a1 individuals he has one unique mutation: A10283G.

The Sorani Kurd is sharing two mutations with the Indian samples HM156682(India) Govindaraj: C2836T and G4659A, so this seems to be a new branch of U1a1a.

The latest complete U1a1 sequence is an individual from the Behar study and one individual from Finland:
142783     Britta Laurintytar Kruskopp, Kannus? Suomi
Both belong to U1a1b, a different branch (highlighted in green).

mtDNA Haplogroup U1a1

Today, I want show some data about mtDNA haplogroup U1a1 because U1a1 is relatively rare and there are already two individuals with U1a1 in this Kurdish DNA project. To clarify, the focus of this post is U1a1, not U1a.


The current scientific literature has 9 fully sequenced U1a1's, presented here: 
 2. AY289073(Koraga/India) Ingman-Gyll
3. AY882396(Adygei = Circassian) Achilli-Rengo
4. DQ112932.2(Africa) Kivisild
5. EF556161 Behar2008 (5 out 82 = 6.1% of Iranian Jews)
6. EF657399 mtDNA250(Europe) Herrnstadt
7. EU597497(Adygei = Circassian, Russia) Hartmann
9. GU218692(Greece) FTDNA
10. HM156682(India) Govindaraj
11. HQ615882(Italy) FTDNA 

I should note that one Indian sequence  [EU872049(India) Bhat] was removed from GenBank because the sequence could not be confirmed. So the number of fully sequenced U1a1 is actually 9 and not 10 as presented by Ian Logan on his website (#8 in Ian Logan's list).

I made a lineage tree of the fully sequenced U1a1 samples:

Other data sources:
 
The Armenian DNA project does not have any mtDNA U1a1.
The Arab DNA project does not have any mtDNA U1a1.
The Jewish DNA project does not have any mtDNA U1a1.
The Assyrian DNA project does not have any mtDNA U1a1.

The Finland DNA project has 2 individuals with U1a1:
142783     Britta Laurintytar Kruskopp, Kannus? Suomi
213047 Thors
 
The global mtDNA haplogroup U1 project has 3 individuals (the Finnish sample same as above):
1 x Barbados
1 x Finland (142783 Britta Laurintytar Kruskopp, Kannus? Suomi)
1 x unknown

At 23andme there are at least 8 individuals with mtDNA U1a1:
1 x Zaza (from Turkey)
1 x Sorani (from Iraq)
1 x Assyrian (from Hakkari/Turkey)
1 x Turk (with maternal Circassian ancestry from Malatya)
1 x from Bethlehem
3 x Americans (unknown ancestry; from US and Canada)