A new paper in Nature (Allentoft et al., 2015) presenting the genomes of ancient 101 Eurasians is currently fascinating geneticists but also linguists and historians. Some of these tested Bronze Age individuals lived in nowadays Armenia.
Here, I want to use their Dodecad K12b values (shared by Mfa from Corduene.blogspot.com) to calculate the closest reference populations for these individuals. Most of the tested individuals from Armenia can be resembled the best as 50-75% Iranian (including Kurds) or Lezgin and 25-50% European. In most cases, Kurds and especially Zaza are among the Top10 reference populations for these ancient genomes, see data below.
In terms of genetic composition the Southern Caucasus was more Iranian-like and European-like than it is today. The shift from Bronze Age to now could be explained by several Semitic empires and three Semitic religions (Judaism, Christianity and Islam) that expanded from South to North and probably impacted local populations of the Northern Middle East.
Interestingly, when traveling through Kurdistan a phenotypic gradient can be seen depending on the altitude: populations from hidden villages in the higher Mountains appear to have lighter skin (and lighter eye color) than the populations from towns in the valleys. Kurds also claim that in ancient times their people were more fair-skinned than they are today.
I believe the same (more Iranian-like and European-like than it is today) will be seen for genomes from Kurdistan. I also believe that the European-like character South of the Caucasus was introduced before the Neolithic expansion, hopefully, ancient DNA will prove this one day. As I mentioned earlier I believe that R1a and R1b originated in or near Kurdistan; two of the Bronze Age samples from Armenia are R1b (RISE397 and RISE413).
RISE413 MBA (1906 BC):
TOP reference populations based on Dodecad K12b:
1 19.6 Turkmens_Y
2 20.2 Turkish_Aydin_Ho
3 20.7 Zaza_P
4 21.0 Turkish_Istanbul_Ho
5 21.3 Turkish_Kayseri_Ho
6 21.4 Tajiks_Y
7 21.7 Iranians
8 21.9 Iranian_D
9 22.1 Kurd_D
10 22.5 Kurds_Y
Oracle K12B:
# Distance
1 7.2639 69.1% Iranians + 30.9% Orcadian
2 7.2701 69.2% Iranians + 30.8% Orkney_1KG
3 7.2770 69% Iranians + 31% Irish_D
4 7.3007 68% Iranians + 32% CEU30
5 7.3294 68.1% Iranians + 31.9% English_D
6 7.3327 67.9% Kurd_D___ + 32.1% Argyll_1KG
7 7.3436 66.4% Iranians + 33.6% Mixed_Germanic_D
8 7.3579 68.4% Iranians + 31.6% Cornwall_1KG
9 7.3697 67.9% Iranians + 32.1% Kent_1KG
10 7.4109 68.1% Iranian_D + 31.9% Argyll_1KG
RISE416 MBA (1643 BC):
1 16.8 O_Italian_D
2 18.4 TSI30
3 18.5 N_Italian_D
4 18.9 Tuscan
5 19.3 C_Italian_D
6 20.5 North_Italian
7 22.7 S_Italian_Sicilian_D
8 23.2 Greek_D
9 23.4 Sicilian_D
10 24.7 Baleares_1KG
Oracle K12B:
# Distance
1 7.2386 75.3% N_Italian_D + 24.7% Balochi
2 7.4475 74.6% N_Italian_D + 25.4% Makrani
3 7.6021 77% N_Italian_D + 23% Brahui
4 7.6188 77% TSI30 + 23% Brahui
5 7.6521 52.4% Lezgins__ + 47.6% Pais_Vasco_1KG
6 7.6804 55% Kurds_Y___ + 45% Pais_Vasco_1KG
7 7.6909 73.3% North_Italian + 26.7% Balochi
8 7.8920 75.5% TSI30 + 24.5% Balochi
9 7.9160 55.2% Iranian_D + 44.8% Pais_Vasco_1KG
10 7.9334 72.6% North_Italian + 27.4% Makrani
RISE423 MBA (1402 BC):
1 14.8 Kumyks_Y
2 15.5 Turkish_Istanbul_Ho
3 16.1 Lezgins__
4 16.5 Turkish_Aydin_Ho
5 16.8 Turkish_Kayseri_Ho
6 16.9 Zaza_P___
7 18.5 Turks___
8 18.9 Turkish_D
9 19.0 Kurds_Y___
10 19.1 Chechens_Y
Oracle K12B:
# Distance
1 4.6697 73.6% Kurds_Y___ + 26.4% Belorussian
2 4.6825 72.5% Kurds_Y___ + 27.5% Mixed_Slav_D
3 4.7566 72.7% Kurds_Y___ + 27.3% Polish_D
4 4.7988 71.3% Kurds_Y___ + 28.7% Ukranians_Y
5 4.8007 73.2% Kurds_Y___ + 26.8% Russian_D
6 4.9732 75.6% Kurds_Y___ + 24.4% Lithuanian_D
7 4.9897 73.2% Kurd_D___ + 26.8% Belorussian
8 5.0133 76.7% Kurds_Y___ + 23.3% Lithuanians
9 5.0365 70.9% Kurd_D___ + 29.1% Ukranians_Y
10 5.0987 72.1% Kurds_Y___ + 27.9% Mordovians_Y
RISE408 LBA (1209 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 18.0 Lezgins__
2 19.3 Kumyks_Y
3 21.4 Turkish_Istanbul_Ho
4 21.5 Turkish_Aydin_Ho
5 22.0 Chechens_Y
6 22.6 Turkish_Kayseri_Ho
7 22.7 Turkmens_Y
8 23.0 Zaza_P___
9 24.0 Tajiks_Y
10 24.3 Iranian_D
Oracle:
# Distance
1 4.7378 79.2% Lezgins__ + 20.8% French_Basque
2 5.2651 72.7% Lezgins__ + 27.3% Cataluna_1KG
3 5.5218 73.7% Lezgins__ + 26.3% Valencia_1KG
4 5.5712 73.9% Lezgins__ + 26.1% Cantabria_1KG
5 5.5818 74.3% Lezgins__ + 25.7% Aragon_1KG
6 5.6722 73.8% Lezgins__ + 26.2% Castilla_La_Mancha_1KG
7 5.6816 73.3% Lezgins__ + 26.7% Spanish_D
8 5.7200 73% Lezgins__ + 27% Spaniards
9 5.8826 71.1% Lezgins__ + 28.9% French
10 5.9217 71.1% Lezgins__ + 28.9% French_D
RISE412 LBA (1193 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID1 9.6 Adygei
2 11.2 Balkars_Y
3 11.7 Kumyks_Y
4 11.8 North_Ossetians_Y
5 13.1 Chechens_Y
6 13.2 Turks___
7 13.2 Turkish_D
8 14.1 Armenians
9 14.7 Turkish_Istanbul_Ho
10 15.8 Armenians_15_Y
11 16.2 Armenian_D
12 16.4 Turkish_Kayseri_Ho
13 17.5 Lezgins__
14 18.3 Abhkasians_Y
15 18.5 Georgia_Jews
16 18.7 Zaza_P___
Oracle K12B:
# Distance
1 3.6433 77.2% Adygei + 22.8% Sephardic_Jews
2 4.0513 77.5% Adygei + 22.5% S_Italian_Sicilian_D
3 4.0932 76.4% Adygei + 23.6% Ashkenazi_D
4 4.1480 75.4% Adygei + 24.6% Ashkenazy_Jews
5 4.2166 77.9% Adygei + 22.1% Sicilian_D
6 4.2440 80% Adygei + 20% Morocco_Jews
7 4.3430 64.7% Chechens_Y + 35.3% Cypriots
8 4.6281 60.3% Adygei + 39.7% Turkish_D
9 4.8258 75% Adygei + 25% Druze
10 4.9047 75.9% Adygei + 24.1% Lebanese
11 4.9790 84.3% Armenians + 15.7% Lithuanians
12 5.0526 77.3% Adygei + 22.7% Greek_D
13 5.0618 64.2% Abhkasians_Y + 35.8% Bulgarian_D
14 5.0744 82% Armenians + 18% Russian_B
15 5.0939 83.6% Armenians + 16.4% Lithuanian_D
16 5.1290 78.9% Adygei + 21.1% Syrians
17 5.1671 81.7% Armenians + 18.3% Mordovians_Y
18 5.1701 70.9% Balkars_Y + 29.1% Cypriots
19 5.2275 65.7% Abhkasians_Y + 34.3% Romanians
20 5.2709 67.1% Adygei + 32.9% Turkish_Kayseri_Ho
RISE396 LBA (1192 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 12.0 Turkish_Istanbul_Ho
2 12.6 Kumyks_Y
3 13.5 Turkish_Kayseri_Ho
4 14.5 Turkish_Aydin_Ho
5 14.5 Turkish_D
6 14.6 Turks___
7 15.3 Zaza_P___
8 16.1 Lezgins__
9 17.1 Chechens_Y
10 18.1 Kurds_Y___
Oracle K12B:
# Distance
1 4.2060 58.2% Lezgins__ + 41.8% Greek_D
2 4.4492 61.5% Lezgins__ + 38.5% Sicilian_D
3 4.5387 60.3% Lezgins__ + 39.7% Ashkenazi_D
4 4.7105 63.8% Lezgins__ + 36.2% C_Italian_D
5 4.7696 58.9% Lezgins__ + 41.1% Ashkenazy_Jews
6 5.2481 63.3% Lezgins__ + 36.7% O_Italian_D
7 5.4614 66.2% Lezgins__ + 33.8% Tuscan
8 5.5673 67% Lezgins__ + 33% TSI30
9 5.8915 62.9% Lezgins__ + 37.1% Sephardic_Jews
10 6.0393 58% Kurds_Y___ + 42% Bulgarian_D
RISE407 LBA (1115 BC):
TOP reference populations based on Dodecad K12b:
# Distance ID
1 19.1 Lezgins__
2 19.6 Turkmens_Y
3 20.0 Tajiks_Y
4 20.7 Kumyks_Y
5 21.3 Zaza_P___
6 21.6 Turkish_Aydin_Ho
7 21.7 Turkish_Istanbul_Ho
8 22.0 Iranian_D
9 22.5 Kurd_D___
10 22.5 Kurds_Y___
Oracle K12B:
# Distance
1 9.0414 77.7% Lezgins__ + 22.3% Pais_Vasco_1KG
2 9.1657 70.8% Iranian_D + 29.2% Norwegian_D
3 9.4091 70.2% Kurd_D___ + 29.8% Swedish_D
4 9.4630 79.2% Lezgins__ + 20.8% French_Basque
5 9.5599 70.4% Kurd_D___ + 29.6% Norwegian_D
6 9.6359 70.1% Kurds_Y___ + 29.9% Swedish_D
7 9.6374 71.4% Lezgins__ + 28.6% Portuguese_D
8 9.6513 72.7% Lezgins__ + 27.3% Cataluna_1KG
9 9.6726 71.2% Lezgins__ + 28.8% Extremadura_1KG
10 9.6800 73.6% Lezgins__ + 26.4% Castilla_La_Mancha_1KG
Friday, June 12, 2015
Tuesday, February 24, 2015
Lactose intolerance: Six MCM6 variants in the Kurdish gene pool / Why 22018A is strongly, but not completely related to lactase persistence
In a previous post I
discussed the possibility of unknown MCM6 haplotypes in Middle Eastern
populations that could lead to lactose tolerance. I wrote:
Not all lactose tolerance SNPs are known, several SNPs resulting in lactose tolerance still need to be discovered.
Today, I want to present 6 haplotypes (ht1-6) I could discover in the Kurdish gene pool.
ht3 represents the "European" haplotype which correlates with lactose tolerance. Individuals with "CT" or "TT" at rs4988235 (also called C/T-13910) are genetically lactose tolerant; at 23andme it is "AG" or "AA" (because MCM6 gene is in minus orientation but 23andme does not address it).
Interestingly, 13910T (rs4988235: "A" at 23andme) and 22018A (rs182549: "T" at 23andme) are strongly linked with one another, at least for ht3, the "European" haplotype. However, this is not always the case. There is some literature about 22018A, see here, here, here, and here.
ht3 itself is derived from ht2, which only carries the 22018A mutation. ht2 is fairly rare and does not provide lactase persistence which explains why 22018A is strongly, but not completely related to lactase persistence.
The origin of the "European" lactose persistence 13910T (rs4988235: "A" at 23andme) can be found in populations where the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3).
In Kurds (N=20) the frequency of 22018A is 8% (ht2 + ht3), the frequency of 13910T is 5% (ht3). Both, ht2 and ht3 are derived from ht1, which has a frequency of 20% among Kurds.
Raz et al., 2013 found that Iraqi Jews (N=96) have a frequency 8.3% for 22018A (ht2 + ht3) and 3.6% for 13910T (ht3), which fits quite well with the Kurdish results.
Find below the frequency of the six MCM6 haplotypes in the Kurdish gene pool:
Find below the six haplotypes (ht1 - ht6) identified in the Kurdish gene pool (ht7 was identified in the Denisova genome. The coverage of the Neanderthal genome was too low to identify the haplotype.)
Find below the phylogenetic tree of MCM6 haplotypes.
Coehlo et al., 2005 predicted that 22018A mutation occured prior to the 13910T mutation.
Bersaglieri et al., 2004 provided the frequency of both 22018A and 13910T in various populations showing that the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3) in Pakistan (excluding Kalash).
Summary:
ht2 (22018A only) is the ancestor of ht3 (22018A + 13910T). ht2 can be found among Kurds, Iraqi Jews and Pakistanis.
I suspect that lactase persistence is also present among a subgroup of ht6.
Not all lactose tolerance SNPs are known, several SNPs resulting in lactose tolerance still need to be discovered.
Today, I want to present 6 haplotypes (ht1-6) I could discover in the Kurdish gene pool.
ht3 represents the "European" haplotype which correlates with lactose tolerance. Individuals with "CT" or "TT" at rs4988235 (also called C/T-13910) are genetically lactose tolerant; at 23andme it is "AG" or "AA" (because MCM6 gene is in minus orientation but 23andme does not address it).
Interestingly, 13910T (rs4988235: "A" at 23andme) and 22018A (rs182549: "T" at 23andme) are strongly linked with one another, at least for ht3, the "European" haplotype. However, this is not always the case. There is some literature about 22018A, see here, here, here, and here.
ht3 itself is derived from ht2, which only carries the 22018A mutation. ht2 is fairly rare and does not provide lactase persistence which explains why 22018A is strongly, but not completely related to lactase persistence.
The origin of the "European" lactose persistence 13910T (rs4988235: "A" at 23andme) can be found in populations where the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3).
In Kurds (N=20) the frequency of 22018A is 8% (ht2 + ht3), the frequency of 13910T is 5% (ht3). Both, ht2 and ht3 are derived from ht1, which has a frequency of 20% among Kurds.
Raz et al., 2013 found that Iraqi Jews (N=96) have a frequency 8.3% for 22018A (ht2 + ht3) and 3.6% for 13910T (ht3), which fits quite well with the Kurdish results.
Find below the frequency of the six MCM6 haplotypes in the Kurdish gene pool:
| ht1 | ht2 | ht3 | ht4 | ht5 | ht6 |
| 20% | 3% | 5% | 15% | 10% | 48% |
Find below the six haplotypes (ht1 - ht6) identified in the Kurdish gene pool (ht7 was identified in the Denisova genome. The coverage of the Neanderthal genome was too low to identify the haplotype.)
| SNP | ht1 | ht2 | ht3 | ht4 | ht5 | ht6 | ht7 |
| rs4988283 | C | C | C | C | C | C | C |
| rs4988262 | C | C | C | C | C | C | T |
| rs2082730 | T | T | T | T | T | T | T |
| rs4988243 | T | T | T | T | C | T | T |
| rs4954492 | A | A | A | A | A | A | A |
| rs41525747 | G | G | G | G | G | G | G |
| rs4988236 | G | G | G | G | G | G | G |
| rs4988235 | G | G | A | G | G | G | G |
| rs41380347 | A | A | A | A | A | A | A |
| rs4988234 | C | C | C | C | C | C | C |
| rs4988233 | G | G | G | G | G | G | G |
| rs2304369 | G | G | G | G | G | G | G |
| rs4988232 | G | G | G | G | G | G | G |
| rs4988226 | G | G | G | A | A | A | A |
| rs309180 | A | A | A | G | G | G | G |
| rs309181 | G | G | G | C | C | C | C |
| rs3213871 | C | C | C | T | T | C | C |
| rs4988203 | C | C | C | C | C | C | T |
| rs182549 | C | T | T | C | C | C | C |
| rs4988199 | A | A | A | A | A | A | A |
| rs4988189 | T | T | T | T | T | T | T |
| rs4988186 | G | G | G | G | G | G | G |
| rs309176 | C | C | C | T | T | T | T |
| rs3087343 | T | T | T | T | T | G | T |
| rs4988177 | T | T | T | T | T | T | T |
| rs3087353 | C | C | C | C | C | C | T |
| rs2289049 | G | G | G | G | G | G | A |
| rs2070068 | G | G | G | G | G | G | A |
| rs1435577 | C | C | C | C | C | G | C |
| rs3769001 | A | A | A | A | A | G | A |
| rs1057031 | G | G | G | G | G | A | A |
Find below the phylogenetic tree of MCM6 haplotypes.
Coehlo et al., 2005 predicted that 22018A mutation occured prior to the 13910T mutation.
Bersaglieri et al., 2004 provided the frequency of both 22018A and 13910T in various populations showing that the frequency of 22018A (ht2 + ht3) is higher than 13910T (ht3) in Pakistan (excluding Kalash).
ht2 (22018A only) is the ancestor of ht3 (22018A + 13910T). ht2 can be found among Kurds, Iraqi Jews and Pakistanis.
I suspect that lactase persistence is also present among a subgroup of ht6.
Thursday, January 15, 2015
Balaresque et al., 2015 (R1a)
Today, I want to identify R1a1 individuals that have the same STR8 haplotype (DYS393, DYS390, DYS19, DYS391, DYS439, DYS389i, DYS392, DYS389ii) as DS2 and DS15 in the recently published paper of Balaresque et al., 2015. Note that STR data have very limited information.
DS2 (perfect matches):
Dubai92 from Alshamali et al., 2009.
297613 Petr Sergeev Slyadnev, 1697, Oboyanskiy uezd R-CTS3402 (FTDNA)
230707 Philippe Renouf b 2/8/1730 Jersey R-Z284 (FTDNA)
349718 Iver Hansen Årholt, 1771, Stokke, VFL R-M512 (FTDNA)
M6619 R-Z93 (FTDNA)
243297 R-L657 (FTDNA)
163435 sayak 14с., kyrgyz R-M173 (FTDNA)
245562 R-M173 (probably Kyrgyz) (FTDNA)
220512 R-M173 (probably Kyrgyz) (FTDNA)
220490 R-M173 (probably Kyrgyz) (FTDNA)
220481 R-M173 (probably Kyrgyz) (FTDNA)
245558 R-M173 (probably Kyrgyz) (FTDNA)
249622 saribaghish (kyrgyz), KG R-M512 (FTDNA)
71094 Samuel Duncan, d.1679/80 MA R-M17 (FTDNA)
DS15 (perfect matches):
Qandahar/South Afghanistan (Sample Afg83) R1a1a* M198 from Lacau et al., 2012
Filipino (Sample431) from Hwa et al., 2010
Izeh [Bakhtiari] (Sample235) from Roewer et al., 2009
Nepal (Kathmandu) R1a1*-M17 (Sample NplK19) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK31) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK40) from Gayden et al., 2011
Nepal (Newar) R1a1*-M17 (Sample NplN67) from Gayden et al., 2011
N89389 Franz Gromann, b. about 1775 R-M512 (FTDNA)
N34838 Stephan Beres R-M198 (FTDNA)
256915 Mieczyslaw Seroka, Lublin province R-M417 (FTDNA)
200664 Simon Netke,abt 1686 -1735 R-M512 (FTDNA)
N47039 Otto Julius Madsen 1896 R-M417 (FTDNA)
264572 Franciscus Zloklikovits,b 1790 Eisenhuttl, Hungary R-CTS3402 (FTDNA)
127728 Andras Dutzman b. 1855 Levart Gemerska Slovakia R-M512 (FTDNA)
131773 Thomas Madon, Illinois? 1941? R-M512 (FTDNA)
N50210 Edmund Trawicki, geb. 1893, Legbad, Pomerania R-F2686 (FTDNA)
E13973 R-M512 (FTDNA)
191976 Mikita Kapustin, b. 1587, Novosil, Russia R-M417 (FTDNA)
257106 Lauri Heikinpoika Häyrinen, b. 1600, Joroinen R-M512 (FTDNA)
188784 Venedikt Vorotyntsev, b.ab.1660, N.Devitsa, Russia R-CTS456 (FTDNA)
283752 Yakim Loboda 1700 - 1750 R-M512 (FTDNA)
313105 Rönn R-Z92 (FTDNA)
201068 Porfyriy Skvortsov, ?-ca.1920, Radalivka, Ukraine R-Z92 (FTDNA)
140423 Olaf Andersson 1676-1759 Hemsjö Alingsås (O) R-M512 (FTDNA)
N23825 Jurgen Kolbe, b.c.1675, Angermunde, Brandenburg,Pr R-Z284 (FTDNA)
283402 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
283403 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
274445 Kete — Aidar — Azhibai — Seyit — Omar R-Z93 (FTDNA)
274482 Kete — Aidar — Azhibai — Seyit — Alkerey R-M512 (FTDNA)
192072 Adamyan, Aintab, Turkey R-Z93 (FTDNA)
N94836 Mr. İlyas Çiloğlu R-Z94 (FTDNA)
322561 Venkayya, b. 1830 R-M512 (FTDNA) 235474 R-M512 (FTDNA)
235471 R-M512 (FTDNA)
M8466 R-CTS3402 (FTDNA) M8458 R-PAGES00007 (FTDNA)
186386 need earliest known paternal ancestor info R-M198 (FTDNA)
245563 R-M512 (FTDNA)
336409 Solto-Tœlœk R-M512 (FTDNA) 219713 Sayak ~14c R-M512 (FTDNA)
277359 Malkarov, Balkaria (Chegem→Baskhan) R-F1345 (FTDNA)
221211 R-M512 (FTDNA) 20409 Gerd Bonorden born about 1500 Bielfel Germany R-M512 (FTDNA)
295213 John T. Windsor, b. 1839 (IN), d. 1924 (MO) R-Z94 (FTDNA)
M8568 R-M512 (FTDNA)
N3798 Raghavendra Kamath 1913-1989 Karkal India R-Z94 (FTDNA)
306446 Aslan Hadji,gf of İ.Akbaev,Chokuna Efendi,Karachay R-M512 (FTDNA)
237819 Abraham Kennedy, b. 1858, Vilnius; d. U.S./Poland R-M512 (FTDNA)
255385 Samuel Duncan, b 1619 and d April 1680 R-M512 (FTDNA)
188766 R-M198 (FTDNA) 177329 R-M512 (FTDNA)
N112185 Ayyapankave Ramakrishna Krishmamurthy, b1926, Ayya R-M512 (FTDNA)
306019 ataul Tiyrnakla, Bayramuk, Karachay R-M512 (FTDNA)
336372 R-M512 (FTDNA)
N87639 Lemuel Murry,1826 -1909 Milton, Rutherford Co.TN R-M17 (FTDNA)
120827 Samuel Irvine, 1789, Limavady, County Londonderry R-M512 (FTDNA)
208262 Fernando Domingo Gutierrez, b. abt 1825 R-M512 (FTDNA)
Edit 01/16.2015:
I started to read the paper. In the supplementary table 3 it provides the number of individuals of each region belonging to a specific DC. I focused on Cinnioglu et al., 2004 data that is included in the supplementary table 3. It claims that in East Anatolia (region 4) 9 out 82 belong to DC2. There are only 9 individuals in region 4, none of them is a perfect match. I realized that only 5 out of 8 STRs need to be identical to belong to DC2 (this is a pretty vague cluster). Using this vague rule I identified more than 800 individuals that are within cluster DC2, a lot of them are not within Z93 and from Europe (Z282+ individuals):
https://docs.google.com/spreadsheets/d/1V5Wumf-nP5NNn1Y57GTxuAw2_cU2XA5pqe4MWzT6Dpo/edit?usp=sharing
Overall, this suggests that data using STR values have very little value, no matter where it is published, especially when it is about vague clusters based on 8 STRs only.
Edit2 01/16.2015:
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 1792 out of 3418 belonging to DC2 (52.4%).
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 2668 out of 3418 belonging to DC15 (78.1%).
This highlights that STR values cannot substitute SNPs.
DS2 (perfect matches):
Dubai92 from Alshamali et al., 2009.
297613 Petr Sergeev Slyadnev, 1697, Oboyanskiy uezd R-CTS3402 (FTDNA)
230707 Philippe Renouf b 2/8/1730 Jersey R-Z284 (FTDNA)
349718 Iver Hansen Årholt, 1771, Stokke, VFL R-M512 (FTDNA)
M6619 R-Z93 (FTDNA)
243297 R-L657 (FTDNA)
163435 sayak 14с., kyrgyz R-M173 (FTDNA)
245562 R-M173 (probably Kyrgyz) (FTDNA)
220512 R-M173 (probably Kyrgyz) (FTDNA)
220490 R-M173 (probably Kyrgyz) (FTDNA)
220481 R-M173 (probably Kyrgyz) (FTDNA)
245558 R-M173 (probably Kyrgyz) (FTDNA)
249622 saribaghish (kyrgyz), KG R-M512 (FTDNA)
71094 Samuel Duncan, d.1679/80 MA R-M17 (FTDNA)
DS15 (perfect matches):
Qandahar/South Afghanistan (Sample Afg83) R1a1a* M198 from Lacau et al., 2012
Filipino (Sample431) from Hwa et al., 2010
Izeh [Bakhtiari] (Sample235) from Roewer et al., 2009
Nepal (Kathmandu) R1a1*-M17 (Sample NplK19) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK31) from Gayden et al., 2011
Nepal (Kathmandu) R1a1*-M17 (Sample NplK40) from Gayden et al., 2011
Nepal (Newar) R1a1*-M17 (Sample NplN67) from Gayden et al., 2011
N89389 Franz Gromann, b. about 1775 R-M512 (FTDNA)
N34838 Stephan Beres R-M198 (FTDNA)
256915 Mieczyslaw Seroka, Lublin province R-M417 (FTDNA)
200664 Simon Netke,abt 1686 -1735 R-M512 (FTDNA)
N47039 Otto Julius Madsen 1896 R-M417 (FTDNA)
264572 Franciscus Zloklikovits,b 1790 Eisenhuttl, Hungary R-CTS3402 (FTDNA)
127728 Andras Dutzman b. 1855 Levart Gemerska Slovakia R-M512 (FTDNA)
131773 Thomas Madon, Illinois? 1941? R-M512 (FTDNA)
N50210 Edmund Trawicki, geb. 1893, Legbad, Pomerania R-F2686 (FTDNA)
E13973 R-M512 (FTDNA)
191976 Mikita Kapustin, b. 1587, Novosil, Russia R-M417 (FTDNA)
257106 Lauri Heikinpoika Häyrinen, b. 1600, Joroinen R-M512 (FTDNA)
188784 Venedikt Vorotyntsev, b.ab.1660, N.Devitsa, Russia R-CTS456 (FTDNA)
283752 Yakim Loboda 1700 - 1750 R-M512 (FTDNA)
313105 Rönn R-Z92 (FTDNA)
201068 Porfyriy Skvortsov, ?-ca.1920, Radalivka, Ukraine R-Z92 (FTDNA)
140423 Olaf Andersson 1676-1759 Hemsjö Alingsås (O) R-M512 (FTDNA)
N23825 Jurgen Kolbe, b.c.1675, Angermunde, Brandenburg,Pr R-Z284 (FTDNA)
283402 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
283403 Kete — Aidar — Azhibai — Seyit — Alseyit R-M512 (FTDNA)
274445 Kete — Aidar — Azhibai — Seyit — Omar R-Z93 (FTDNA)
274482 Kete — Aidar — Azhibai — Seyit — Alkerey R-M512 (FTDNA)
192072 Adamyan, Aintab, Turkey R-Z93 (FTDNA)
N94836 Mr. İlyas Çiloğlu R-Z94 (FTDNA)
322561 Venkayya, b. 1830 R-M512 (FTDNA) 235474 R-M512 (FTDNA)
235471 R-M512 (FTDNA)
M8466 R-CTS3402 (FTDNA) M8458 R-PAGES00007 (FTDNA)
186386 need earliest known paternal ancestor info R-M198 (FTDNA)
245563 R-M512 (FTDNA)
336409 Solto-Tœlœk R-M512 (FTDNA) 219713 Sayak ~14c R-M512 (FTDNA)
277359 Malkarov, Balkaria (Chegem→Baskhan) R-F1345 (FTDNA)
221211 R-M512 (FTDNA) 20409 Gerd Bonorden born about 1500 Bielfel Germany R-M512 (FTDNA)
295213 John T. Windsor, b. 1839 (IN), d. 1924 (MO) R-Z94 (FTDNA)
M8568 R-M512 (FTDNA)
N3798 Raghavendra Kamath 1913-1989 Karkal India R-Z94 (FTDNA)
306446 Aslan Hadji,gf of İ.Akbaev,Chokuna Efendi,Karachay R-M512 (FTDNA)
237819 Abraham Kennedy, b. 1858, Vilnius; d. U.S./Poland R-M512 (FTDNA)
255385 Samuel Duncan, b 1619 and d April 1680 R-M512 (FTDNA)
188766 R-M198 (FTDNA) 177329 R-M512 (FTDNA)
N112185 Ayyapankave Ramakrishna Krishmamurthy, b1926, Ayya R-M512 (FTDNA)
306019 ataul Tiyrnakla, Bayramuk, Karachay R-M512 (FTDNA)
336372 R-M512 (FTDNA)
N87639 Lemuel Murry,1826 -1909 Milton, Rutherford Co.TN R-M17 (FTDNA)
120827 Samuel Irvine, 1789, Limavady, County Londonderry R-M512 (FTDNA)
208262 Fernando Domingo Gutierrez, b. abt 1825 R-M512 (FTDNA)
Edit 01/16.2015:
I started to read the paper. In the supplementary table 3 it provides the number of individuals of each region belonging to a specific DC. I focused on Cinnioglu et al., 2004 data that is included in the supplementary table 3. It claims that in East Anatolia (region 4) 9 out 82 belong to DC2. There are only 9 individuals in region 4, none of them is a perfect match. I realized that only 5 out of 8 STRs need to be identical to belong to DC2 (this is a pretty vague cluster). Using this vague rule I identified more than 800 individuals that are within cluster DC2, a lot of them are not within Z93 and from Europe (Z282+ individuals):
https://docs.google.com/spreadsheets/d/1V5Wumf-nP5NNn1Y57GTxuAw2_cU2XA5pqe4MWzT6Dpo/edit?usp=sharing
Overall, this suggests that data using STR values have very little value, no matter where it is published, especially when it is about vague clusters based on 8 STRs only.
Edit2 01/16.2015:
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 1792 out of 3418 belonging to DC2 (52.4%).
In the current FTDNA R1a1a and Subclades Y-DNA Project I identified 2668 out of 3418 belonging to DC15 (78.1%).
This highlights that STR values cannot substitute SNPs.